Results 201 to 210 of about 112,908 (344)

Establishment of a novel alloxan‐induced rabbit model exhibiting unique diabetic retinal neuropathy features assessed via ERG + VEP

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Study workflow. Neuroretinal changes were observed in alloxan‐induced diabetic rabbits, while the retinal vasculature remained unaffected, indicating the successful establishment of a diabetic neuroretinal model. Abstract Background Diabetic retinal neuropathy (DRN) leads to significant visual impairment; however, no existing animal model fully ...
Xinlu Li   +9 more
wiley   +1 more source

The Spectrum of Neurologic Phenotypes Associated With NUS1 Pathogenic Variants: A Comprehensive Case Series

open access: yesAnnals of Neurology, EarlyView.
Objective A growing body of evidence indicates a strong genetic overlap between developmental and epileptic encephalopathies (DEEs) and movement disorders. De novo loss‐of‐function variants in NUS1 have been recently identified in DEE cases. Herein, we report a large cohort of cases with pathogenic NUS1 variants and describe their clinical presentation
Sarah M. Brooker   +79 more
wiley   +1 more source

Oral Delivery of Chitosan‐Rosmarinic Acid Nanoparticles Ameliorates Mucosal Inflammation in a Mouse Model of Colitis

open access: yesAdvanced NanoBiomed Research, EarlyView.
Orally administered low molecular weight chitosan–rosmarinic acid nanoparticles demonstrate potent anti‐inflammatory effects in a mouse model of colitis by scavenging reactive oxygen species, preserving intestinal barrier integrity, and modulating immune responses, underscoring their promise as an effective nanomedicine for inflammatory bowel disease ...
Afia Tasnim Rahman   +2 more
wiley   +1 more source

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