Results 261 to 270 of about 113,083 (340)

Oral Delivery of Chitosan‐Rosmarinic Acid Nanoparticles Ameliorates Mucosal Inflammation in a Mouse Model of Colitis

open access: yesAdvanced NanoBiomed Research, EarlyView.
Orally administered low molecular weight chitosan–rosmarinic acid nanoparticles demonstrate potent anti‐inflammatory effects in a mouse model of colitis by scavenging reactive oxygen species, preserving intestinal barrier integrity, and modulating immune responses, underscoring their promise as an effective nanomedicine for inflammatory bowel disease ...
Afia Tasnim Rahman   +2 more
wiley   +1 more source

Stability and Release Characteristics of Core‐Shell Beads with Emulsion Core Under Gastrointestinal Conditions

open access: yesAdvanced NanoBiomed Research, EarlyView.
A combined emulsion–core‐shell structure system is developed for targeted delivery of lipophilic compounds to the proximal intestine. Using vitamin D3‐loaded sunflower oil emulsions, the core‐shell structure enhances droplet stability, encapsulation efficiency, and gastric protection.
Fariba Malekpour Galogahi   +3 more
wiley   +1 more source

Multiplexed Cutaneous Wound Monitor for Point‐of‐Care Applications

open access: yesAdvanced NanoBiomed Research, EarlyView.
Wearable monitors are poised to transform wound care, easing healthcare burdens. These devices integrate sensors and wireless capabilities, enabling continuous, remote monitoring. This work showcases a flexible, wireless system‐on‐chip that tracks C‐reactive protein (CRP), interleukin‐6 (IL‐6), pH, and temperature.
Peter Francis Mathew Elango   +10 more
wiley   +1 more source

Nanodroplet Array Platform for Integrated Synthesis and Screening of MEK Inhibitors: a Miniaturized Approach to Early Drug Discovery

open access: yesAngewandte Chemie International Edition, EarlyView.
We present a nanodroplet array platform that integrates solid‐phase synthesis, MALDI‐MS analysis, and cell‐based screening. Using nanoliter droplets, we synthesized and tested 325 potential MEK inhibitors and identified 46 active compounds. This miniaturized approach combines chemistry and biology on a single chip, reducing time, cost, and material use
Maximilian Seifermann   +10 more
wiley   +1 more source

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