Results 181 to 190 of about 301,607 (199)

Developing a FEES service in South Africa: Interdisciplinary reflections for dysphagia care. [PDF]

S Afr J Commun Disord
Barber N, Capon T, De Lira de Gouveia M, Radebe N.   +3 more
europepmc   +1 more source

Zuranolone: A case study in (regulatory) rush to judgement?

British Journal of Clinical Pharmacology, EarlyView.
Abstract Sage, in collaboration with Biogen, submitted a new drug approval for zuranolone for postpartum depression (PPD) and major depressive disorder (MDD) in December 2022. In August 2023, the US Food and Drug Administration granted approval for PPD but denied approval for MDD.
Lisa Cosgrove, Milutin Kostic, Barbara Mintzes, Gianna D'Ambrozio, Allen Shaughnessy   +4 more
wiley   +1 more source

Short-term real-world outcomes of switching to faricimab in anti-VEGF-refractory retinal vein occlusion: a prospective study. [PDF]

BMC Ophthalmol
Kilani A, Assaf A, Vogt D, Vounotrypidis E, Parlak M, Jochem C, Wolf A.   +6 more
europepmc   +1 more source

Developing medication independence: The experience of UK teenagers

British Journal of Clinical Pharmacology, EarlyView.
Aims There is a progression through childhood from being provided medications by caregivers to having to take responsibility for medications yourself, but little is known about when the transition of adolescents managing medicines begins. The aim of this study was to obtain a cross‐sectional sample of UK adolescents and when they become independent ...
Holly Hutchins, Charlotte King, Louis Bioletti, Tsegay Gebru, Alder Hey Research Ambassadors, Daniel B. Hawcutt   +5 more
wiley   +1 more source

Real-world evidence of measurable residual disease assessment in multiple myeloma. [PDF]

Blood Adv
Cedena MT, Puig N, Paiva B, de la Puerta JE, Pérez-Montaña A, Casanova M, Breña J, García A, de Arriba F, Martínez-Chamorro C, Sirvent M, Blanchard MJ, Alonso R, Álvarez MÁ, Capote FJ, García-Sánchez R, Pérez JJ, Rodriguez-Otero P, Lahuerta JJ, Martínez-López J, Mateos MV, San-Miguel J.   +21 more
europepmc   +1 more source

Do drugs approved via expedited approval pathways have therapeutic advantages? A systematic review and meta‐analysis

British Journal of Clinical Pharmacology, EarlyView.
Regulators use expedited approval pathways to speed market approval and patient access to promising new drugs. However, there is uncertainty about whether these pathways are successful in approving drugs with significant therapeutic advantages. This systematic review aims to examine the safety, effectiveness and cost‐effectiveness of drugs approved via
Ashleigh Hooimeyer, Eliza J. McEwin, Zhicheng Wang, Joel Lexchin, Barbara Mintzes   +4 more
wiley   +1 more source

Clinical Efficacy of One Short Course of Mannan-Conjugated Birch Pollen Allergoid Immunotherapy: A Comparative Evaluation After Prior Placebo Treatment. [PDF]

J Clin Med
Del Pozo S, Wahrhusen N, Pfaar O, Raskopf E, Rybachuk A, Acikel C, Sahin H, Allekotte S, Subiza JL, Casanovas M, Cuevas M, Mösges R.   +11 more
europepmc   +1 more source

Completion vs. early discontinuation of chemotherapy and the impact on 5‐year all‐cause mortality in women treated for early‐stage breast cancer from 2015 to 2020: A cohort study using a target trial emulation approach

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Chemotherapy is given for early‐stage breast cancer; however, some patients discontinue before completing all planned cycles. This study investigated the impact of early chemotherapy discontinuation on treatment outcomes. Methods This retrospective cohort study used a target trial emulation framework to conduct a causal analysis of the all‐
Luke Steventon, Chengsheng Ju, Kenneth K. C. Man, Rebecca Roylance, Diego Ottaviani, Chiara Creed, Michal Sladkowski, Alec Wisner, Li Wei, Pinkie Chambers   +9 more
wiley   +1 more source

Venetoclax and Blinatumomab for adult patients with relapsed/refractory or MRD positive Ph-negative B-cell precursor ALL: phase I part of the GMALL-BLIVEN trial. [PDF]

Ann Hematol
Fransecky L, Fiedler W, Röllig C, Sauer T, Raffel S, Alsdorf W, Heberling L, Steer B, Huber K, Versteegen T, Spory L, Deckbar D, Reiser L, Bendig S, Bastian L, Bozzetti C, Beder T, Neumann M, Brüggemann M, Gökbuget N, Baldus C.   +20 more
europepmc   +1 more source

Artificial Intelligence to Extract Structured Details From Unstructured Medical Records in a Global Heart Failure Trial. [PDF]

JACC Heart Fail
Badrouchi S, Marti-Castellote PM, Foà A, Claggett BL, Desai AS, Xu D, Ho JE, Ellinor P, Jhund PS, McGrath MM, McCausland FR, McMurray JJV, Solomon SD, Cunningham JW.   +13 more
europepmc   +1 more source