Results 151 to 160 of about 183,999 (245)

Management of a Missed Iatrogenic Fracture Neck of Femur in an Operated Case of Fracture Shaft Femur- Case Report. [PDF]

J Orthop Case Rep
Salgaokar N, Dmello W, Verlekar AS, Dessai SA, Singh N, Sharma S.   +5 more
europepmc   +1 more source

A Nanoparticle‐Integrated Complete Manufacturing Pipeline of Chemically Engineered Exosomes

Advanced Science, EarlyView.
We report a novel manufacture technology of chemically engineered exosomes. The four steps of manufacturing, i.e., biogenesis, loading, isolation, and storage, are integrated by the use of a nanoparticle. The manufacture technology incorporates three innovative components, i.e., a new nano‐bio effect, a new composite nanoparticle, and a new isolation ...
Xiaowei Wen, Zixing Xu, Zerun Hao, Yanming Chen, Kai Xie, Haofan Yin, Xueying Wang, Jie Min, Sihan Sun, Baiding Chen, Chengxiu Ling, Mingming Xu, Yizhao Chen, Gang Ruan   +13 more
wiley   +1 more source

Differences in characteristic morphological variability among distal femurs based on sex and ethnicity. [PDF]

Bone Jt Open
Ammoury N, Dunbar MJ, D'Alessio J, Astephen Wilson J.   +3 more
europepmc   +1 more source

Developmentally Inspired, Mechanical–Metabolic Dual Gradient Osteochondral Constructs Bridging Regeneration and Therapeutic Screening

Advanced Science, EarlyView.
A developmentally inspired osteochondral construct integrates mechanical and metabolic dual gradients within a 3D‐printed platform. Human MSC spheroids are spatially directed to form cartilage–bone interfaces, enabling evaluation of regeneration without biochemical reagents and assessment of drug responses. This physiologically relevant, phase‐specific
Yurim Choi, Wonjun Jang, Raehui Kang, Ulziituya Batjargal, Jihyeon Song, Soojin Park, MinSeok Kim, Hyobum Cho, Junhyung Kim, Yu Shrike Zhang, Han‐Jun Kim, Junmin Lee   +11 more
wiley   +1 more source

Short-interval total femur replacement for infected distal femoral reconstruction. [PDF]

J Surg Case Rep
Chernov D, Frappa N, Dillon M, Kovacs A, Alben M, Riley R, Kuechle JB.   +6 more
europepmc   +1 more source

SLC2A3‐Mediated Lactate Metabolism Promotes Lung Cancer Bone Metastasis by Modulating P53 Lactylation and Immune Evasion

Advanced Science, EarlyView.
SLC2A3 derived lactate promotes metastasis through p53 lactylation at K120 and osteoclast differentiation. Pharmacological inhibition of SLC2A3 upregulates PD‐1 expression on CD8+ T cells via lactate induced p53 lactylation, which modulates immune evasion. ABSTRACT Bone metastasis is a devastating consequence of lung cancer.
Yi Ding, Yuying Tian, Wenjie Ren, Xianglin Hu, Mengjuan Li, Bei Liu, Chen chen, Yunhan Lu, Lei Li, Wangjun Yan, Kun Li   +10 more
wiley   +1 more source

Prenatal Detection of Proximal Femoral Focal Deficiency (PFFD) in Limited Resource Setting: A Case Report. [PDF]

Int Med Case Rep J
Arioseno YA, Pramatirta AY, Caropeboka MFA, Sanjaya MEJ, Adibrata AA.   +4 more
europepmc   +1 more source

Single‐Cell Atlas of Subchondral Bone Marrow Lesions Reveals Proteostasis Dysfunction as a Druggable Mechanism for Early Osteoarthritis

Advanced Science, EarlyView.
This study reveals that abnormal mechanical stress downregulates the expression of HSP70 and impairs proteasome function in osteoarthritic bone cells, leading to misfolded collagen I accumulation and ER stress. When intracellular proteostasis capacity is exceeded, USP19 mediates the secretion of misfolded proteins into the extracellular space ...
Hailun Xu, Ting He, Yu Qian, Jia Li, Bowei Ni, Xiaojie Xu, Huanbo Wang, Peng Wang, Guoqing Cao, Siqi Ying, Guangyu Ding, Rong Wang, Zenghui Gu, Wei Li, Zhentao Man, Houfeng Zheng, Zhaohua Zhu, Zhen Li, Qingjun Meng, Chao Zheng, Liu Yang   +20 more
wiley   +1 more source

Femur fracture: characteristics of patients, treatment outcomes, and factors associated with good outcomes at Gulu Regional Referral Hospital in Uganda. A retrospective review of hospital records of 2022. [PDF]

BMC Res Notes
Okwada I, Longoli I, Ukwang S, Tumuhaise L, Kitara DL.   +4 more
europepmc   +1 more source

Expressão do gene receptor da leptina (LEPR) em frangos de corte normais e afetados pela necrose da cabeça do fêmur. [PDF]

, 2015
IBELLI, A. M. G., LEDUR, M. C., MARCHESI, J. A. P., PALUDO, E., PEIXOTO, J. de O., TAVERNARI, F. de C.   +5 more
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