Results 221 to 230 of about 301,916 (339)

RIPK1 Drives JAK1‐STAT3 Signaling to Promote CXCL1‐Mediated Neutrophil Recruitment in Sepsis‐Induced Lung Injury

Advanced Science, EarlyView.
This article examines the central role of RIPK1 in the pathogenesis of sepsis‐induced lung injury. It elucidates how RIPK1 initiates an inflammatory cascade by activating JAK1‐STAT3 signaling, leading to CXCL1‐mediated neutrophil infiltration. Importantly, it demonstrates that pharmacological inhibition of RIPK1 effectively attenuates inflammation and ...
Hao Sun, Xiya Li, Shenjia Gao, Yi Jiang, Xinyi Wu, Zhaoyuan Chen, Han Wu, Qing Hua, Rui Zu, Huaijiang Xiang, Ronen Ben‐Ami, Changhong Miao, Li Tan, Ying Li, Jun Wang, Wankun Chen   +15 more
wiley   +1 more source

Concomitant Neck of Femur and Greater Trochanter Fracture in a Young Adult - A Case Report. [PDF]

J Orthop Case Rep
Kotangale P, Chaudhary S, Jogani A, Jaiswal N, Sakharkar N, Tarte A.   +5 more
europepmc   +1 more source

Osteonecrose de cabeça de fêmur em paciente portadora de anemia falciforme: Relato de caso

, 2023
Nicole Jenniffer Giffoni Cruz, Stella Maris de Lima Siqueira, Paulo José Oliveira Cortez, Jaqueline Brandão Guerreiro Marotti   +3 more
openalex   +2 more sources

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang, Lihuan Shang, Xiaochun Chen, Xiangzhan Kong, Xiaojuan Wang, Linjia Jiang, Huiying Zhao, Yafeng Zhu, Cheng Huang, Shiyi Deng, Rui Zhang, Minghui Wang, Haoming Lin, Ping‐Pui Wong   +13 more
wiley   +1 more source

Biomechanical comparison of cephalomedullary and reconstruction nails used in the treatment of subtrochanteric femur fractures. [PDF]

OTA Int
McKeeman J, Weiss S, Gomez R, Hast M, Friday C, Higgins M, Lundy D.   +6 more
europepmc   +1 more source

PREVENÇÃO DE QUEDAS EM IDOSOS E MANEJO FISIOTERAPÊUTICO PÓS FRATURA DE FÊMUR

, 2023
Maria Rita Martins do Prado, Lara Luiza Campos de Souza   +1 more
openalex   +1 more source

Precision‐Arranged DNA Origami Plasmonic Nanoantennas for Multidimensional Smart‐Warning of Weightlessness Induced Bone Loss

Advanced Science, EarlyView.
It is synthesized precision‐arranged DNA origami plasmonic nanoantennas for multiplexed and intelligent warning of bone loss induced by microgravity and radiation. The ordered nanoantennas simultaneously and accurately detected calcium ions, interleukin‐6, and microRNA‐214 in serum from mice exposed to microgravity and radiation, with performance ...
Yufan Ling, Xuan Qin, Weijia Sun, Fan Yue, Yiwei Wang, Di Fan, Haoyuan Xu, Ruao Xie, Jiawei Zhang, Jianwei Li, Bingyan Li, Yang Yang, Yingxian Li, Houyu Wang, Guangming Zhou   +14 more
wiley   +1 more source

Increased associated risk of postoperative periprosthetic femur fracture with cementless versus cemented hemiarthroplasty: a nationwide database study of 24,419 femoral neck fractures. [PDF]

OTA Int
Rodgers F, Working ZM, Friess D, Yoo J, Kagan R.   +4 more
europepmc   +1 more source

Condições de saúde dos idosos internados com fratura de fêmur

, 2016
Letí­cia Pilotto Casagranda, Fernanda dos Santos, Celmira Lange, Patrícia Mirapalheta Pereira de Llano, Viviane Martin Milbrath, Andressa Hoffmann Pinto   +5 more
openalex   +1 more source

A Novel Therapeutic Strategy for Bone Marrow Failure: Niche Rejuvenation Using Costal Cartilage‐Derived Stem Cells

Advanced Science, EarlyView.
CDSCs exhibit the potential to differentiate into endothelial cells, vascular pericytes, and osteoblasts. These differentiated cells are capable of secreting additional pro‐hematopoietic cytokines. Furthermore, CDSCs can inhibit apoptosis and reduce DNA damage in injured hematopoietic stem and progenitor cells (HSPCs, including RHSCs and RHPCs), while ...
Rui Dong, Zhiguo Ling, Pengyuan Fan, Debao Li, Jinsong Wang, Wenjiong Shi, Rui Zuo, Runfeng Chen, Xuemin Sun, Lang Xiao, Yushi Ran, Shucheng Huang, Yi Tian, Chao Zhang, Yuzhang Wu, Bing Ni, Yi Zhang   +16 more
wiley   +1 more source