Results 251 to 260 of about 301,916 (339)

Centimeter‐Scale Self‐Assembling Tendon Organoids Drive Tissue Regeneration

open access: yesAdvanced Science, EarlyView.
Centimeter‐scale tendon organoids are engineered by mimicking the extracellular matrix and optimizing chemical cues to guide tendon stem/progenitor cells. These large, self‐assembling constructs overcome conventional size limitations and exhibit enhanced tenogenic differentiation, extracellular matrix production, and mechanical resilience. Their tissue‐
Tianshun Fang   +16 more
wiley   +1 more source

What makes an accurate and reliable subject-specific finite element model? A case study of an elephant femur

open access: yesJournal of the Royal Society Interface, 2014
O. Panagiotopoulou   +4 more
semanticscholar   +1 more source

Inhibition of Macrophage ARID3A Alleviates Myocardial Ischemia‐Reperfusion Injury After Heart Transplantation by Reducing THBS1/CD47 Signaling‐Mediated Neutrophil Extracellular Traps Formation

open access: yesAdvanced Science, EarlyView.
This study reveals that ARID3A in macrophages can transcriptionally regulate the THBS1‐CD47 axis after heart transplantation (HT), thereby inducing activated neutrophils to release NETs through the p38 MAPK signaling pathway. The itaconate derivative 4‐OI can inhibit ARID3A in macrophages and promote the accumulation of antioxidant factors, thereby ...
Hao Tian   +7 more
wiley   +1 more source

Interfacial Coordination‐Engineered Emulgel Modulates the Osteo‐Immune Microenvironment in Periodontitis Treatment Via HIF1 Signaling Pathway‐Induced Metabolic Reprogramming

open access: yesAdvanced Science, EarlyView.
Schematic illustration of HIPPE‐QU‐mediated periodontal regeneration. a) Fabrication process and microstructure of HIPPE‐QU. b) Antimicrobial and immunomodulatory HIPPE‐QU hydrogel for periodontal regeneration. HIPPE‐QU hydrogel co‐delivers HA‐Cu, GNPs, and QU, providing antimicrobial effects and reprogramming the immune microenvironment to promote ...
Hui Zhang   +13 more
wiley   +1 more source

Bone mineral density measurement in the Gruen zones using dual-energy x-ray absorptiometry : insights from quantitative CT analysis. [PDF]

open access: yesBone Joint Res
Uemura K   +9 more
europepmc   +1 more source

Healing Delayed But Generally Reliable After Bisphosphonate-associated Complete Femur Fractures Treated with IM Nails

open access: yesClinical Orthopaedics and Related Research, 2014
K. Egol   +4 more
semanticscholar   +1 more source

The Sirt1‐Piezo1 Axis Promotes Bone Formation and Repair in Mice

open access: yesAdvanced Science, EarlyView.
Piezo1 upregulates in cartilage callus during bone repair, where its deletion impairs ossification and healing in mice, while activation enhances these processes. Sirt1 positively regulates Piezo1 expression and activity to promote osteogenesis and bone repair in mice.
Donghao Gan   +16 more
wiley   +1 more source

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