Results 31 to 40 of about 179,884 (241)

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

A Systematic Review and Meta‐Analysis of the Recurrence of Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune encephalitis (AE) is a disease with a potential for recurrence, and patients receive immunotherapy to prevent it. However, there is no consensus on the duration of immunotherapy. This study aimed to determine the recurrence rate and identify the risk factors for AE to provide guidance on the duration of immunotherapy ...
Shangkai Bai, Sen Zhang, Haipei Zhang, Yating Zhang, Junhong Guo, Xiaoyan Yang   +5 more
wiley   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

Avaliação radiográfica da inserção femoral do ligamento cruzado posterior [PDF]

Acta Ortopédica Brasileira, 2013
OBJETIVO: Determinar as imagens radiográficas da inserção femoral do ligamento cruzado posterior (LCP) para auxiliar na criação de túneis femorais anatômicos nas cirurgias e para a avaliação pós-operatória da localização destes túneis.
Julio Cesar Gali, André Schmidt Soares, Bruno Spagnuolo de Lima, Filippo Santos Zozoloto Vianna, Phelipe Augusto Cintra da Silva, Edie Benedito Caetano   +5 more
doaj   +3 more sources

Nonsurgical Management of Distal Femur Stem Cortical Perforation

Arthroplasty Today, 2020
Distal femur stem cortical perforation is a rare but potentially catastrophic complication during total hip arthroplasty. If unrecognized, it can lead to transverse fracture of the femur while the patient is ambulating.
Minzhi Yang, MD, Jerry Yongqiang Chen, MD, Xiangpeng Kong, MD, Wei Chai, MD   +3 more
doaj   +1 more source

Does Long‐Term Lower Extremity Strength Training in Adults With Knee Osteoarthritis and Varus Alignment Reduce Knee Joint Loading During Gait?

Arthritis Care &Research, EarlyView.
Objective We examined whether 18 months of strength training in individuals with knee varus alignment and medial tibiofemoral osteoarthritis (OA) reduced knee joint loads during walking compared to an attention control group. Methods This study was a secondary analysis of a randomized clinical trial that compared the effects of strength training to a ...
Stephen P. Messier, Matthew N. Vigliotti, Paige E. Rice, Brian Pietrosimone, Shannon L. Mihalko, Edward H. Ip, Richard F. Loeser, David J. Hunter, Ali Guermazi, Ryan Hill, Santiago Saldana, Kim L. Bennell, Paul DeVita   +12 more
wiley   +1 more source

Triangular Index Ratio as an Alternative Method to the Alpha Angle for Defining the Presence of Cam Morphology: A Prospective Cohort Study

Arthritis Care &Research, EarlyView.
Objective Cam morphology, which is a significant risk factor for hip osteoarthritis, is commonly quantified by the alpha angle (AA). This study aims to explore the potential of the triangular index ratio (TIR) to quantify cam morphology on anteroposterior radiographs by assessing the association between TIR‐defined cam morphology and the development of
Jinchi Tang, Fleur Boel, Michiel M. A. van Buuren, Noortje S. Riedstra, Myrthe A. van den Berg, Jos Runhaar, Sita Bierma‐Zeinstra, Rintje Agricola   +7 more
wiley   +1 more source

Osteossíntese de fêmur em gato-do-mato-pequeno (Leopardus tigrinus) Femur osteosynthesis in little spotted cat (Leopardus tigrinus)

Pesquisa Veterinária Brasileira, 2013
O gato-do-mato-pequeno (Leopardus tigrinus) apresenta porte e proporção corporal semelhante ao gato doméstico e é a menor espécie de felídeo não doméstico do Brasil, sendo classificado com espécie da fauna brasileira ameaçada de extinção.
Ísis S. Dal-Bó, Márcio P. Ferreira, Maurício V. Brun, José R. Silva Filho, Fernanda S. Nóbrega, Aparício M. Quadros, João P.S. Feranti, Joana A.B. Chagas   +7 more
doaj  

Atypical femoral fracture due to chronic use of bisphosphonates: case report ☆

Revista Brasileira de Ortopedia, 2015
The causal relationship between chronic use of bisphosphonates and occurrences of atypical femoral fractures has not yet been established. Nonetheless, it is known that their chronic use is more related to fractures with a pattern differing from that of ...
Eduardo Frois Temponi, Lúcio Honório de Carvalho Junior, Lincoln Paiva Costa   +2 more
doaj   +1 more source

Estimation of Length of Femur from its Proximal Segment in Maharashtrian Population [PDF]

International Journal of Anatomy Radiology and Surgery, 2019
Introduction: Stature is an important parameter in identification of an individual. It can be calculated from length of long bones especially femur and tibia. Bony markers such as head and neck of femur can used in determining the length of femur and
Anil Kumar Dwivedi, Niyati Airan, Rajan Bhatnagar   +2 more
doaj   +1 more source