Results 291 to 300 of about 80,011 (352)
Imaging malaria parasites across scales and time
Journal of Microscopy, EarlyView.Abstract The idea that disease is caused at the cellular level is so fundamental to us that we might forget the critical role microscopy played in generating and developing this insight. Visually identifying diseased or infected cells lays the foundation for any effort to curb human pathology.
Julien Guizetti
wiley +1 more source
Seamless, modular binary vectors for plant cell and molecular biology
Plant Biotechnology Journal, EarlyView.Summary In plants, genetic manipulations are commonly performed using Agrobacterium tumefaciens, a plant pathogen whose abilities as a ‘natural genetic engineer’ have been co‐opted for biotechnological applications. In the widely used binary vector systems, Agrobacterium already contains a plasmid with most of the genes needed for virulence and is ...
Rory Greenhalgh +5 more
wiley +1 more source
Performance of chatbots in queries concerning fundamental concepts in photochemistry
Photochemistry and Photobiology, EarlyView.The advent of chatbots raises the possibility of a paradigm shift in many disciplines of scientific research. Here, 13 photochemically relevant queries were posed to five chatbots. The queries include fundamental concepts, practical or philosophical matters, and properties of dyes.
Masahiko Taniguchi, Jonathan S. Lindsey
wiley +1 more source
Photochemistry and Photobiology, EarlyView.Eduardo Lissi, Dorita Adamo‐Lissi and Juan Grotewold in Aberystwyth, Wales, winter 1961. Upon their return to Buenos Aires in 1963, with their PhD degrees, Lissi and Grotewold started a Chemical Kinetics and Photochemistry group in the School of Sciences (University of Buenos Aires).
Silvia E. Braslavsky +1 more
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend The volume‐regulated anion channel (VRAC), composed of leucine‐rich repeat‐containing 8 (LRRC8) proteins, serves both canonical and non‐canonical functions in vertebrate cells. The canonical function of this channel relates to its original description, which is homeostatic regulation of cell volume in response to hypotonic ...
Sergei Yanushkevich +9 more
wiley +1 more source
Sphingosine‐1‐phosphate activates LRRC8 volume‐regulated anion channels through Gβγ signalling
The Journal of Physiology, EarlyView.Abstract figure legend Sphingosine‐1‐phosphate (S1P) binds to Gi protein‐coupled receptor S1PR1. Upon S1PR1 activation, Gβγ is released from the Gαi‐Gβγ heterotrimer, allowing it to recruit phospholipase Cβ (PLCβ) to the plasma membrane. PLCβ cleaves phosphatidylinositol‐4,5‐bisphosphate (PIP2) into inositol trisphosphate (IP3) and diacylglycerol (DAG).
Yulia Kostritskaia +4 more
wiley +1 more source
Recent optical approaches for anatomical and functional dissection of neuron–astrocyte circuitry
The Journal of Physiology, EarlyView.Abstract figure legend This review summarises novel optical approaches to deciphering structural and functional wiring diagrams of neuron–astrocyte circuits in the brain. There are three groups: the anatomical proximity assay, transsynaptic viral tracing and the functional connection assay. The FRET‐based neuron–astrocyte proximity assay allows mapping
Yoshiki Hatashita, Takafumi Inoue
wiley +1 more source