Results 141 to 150 of about 16,694 (193)
pH‐Responsive Ultrasmall Iron Oxide Nanoassemblies for Activatable T2/T1 Magnetic Resonance Imaging
This research reports a pH‐responsive ultrasmall iron oxide nanoparticle (USIONs)/polymer nanoassemblies for activatable magnetic resonance imaging. Amphiphilic diphosphonic acid block copolymers compactly encapsulate USIONs to generate T2‐weighted contrast at physiological pH, while acidic conditions trigger disassembly, activating T1‐weighted ...
Xumin Huang +11 more
wiley +1 more source
Supracolloidal Chains of Patchy Micelles Triggering Förster Resonance Energy Transfer upon Their Growth for Macroscopic Monitoring of Colloidal Assembly. [PDF]
Kim S, Kim K, Kim J, Lee K, Sohn BH.
europepmc +1 more source
Abstract Macromolecular crowding modulates enzyme behavior in crowder‐ and protein‐specific ways, yet its impact on viral proteases, which are often key therapeutic targets, remains unclear. Here, we investigated the hepatitis C virus NS3/4A protease under increasing concentrations of polyethylene glycols (PEGs), ficoll, dextran, and lysozyme using ...
Małgorzata Lobka, Joanna Trylska
wiley +1 more source
A Förster Resonance Energy Transfer (FRET)-based System Provides Insight into the Ordered Assembly of Yeast Septin Hetero-octamers. [PDF]
Booth EA, Vane EW, Dovala D, Thorner J.
europepmc +1 more source
Quantitative and amino acid sequence analysis of soluble HIV‐1 Vpu and calmodulin interactions
Abstract HIV‐1 Vpu supports viral adaptation through host‐protein interactions. Although mainly membrane‐associated, we recently identified a soluble Vpu form that forms a stable complex with Ca2+‐bound calmodulin (Ca2+–CaM), potentially influencing Vpu trafficking. Here, to determine the binding affinity and identify regions of soluble Vpu involved in
Adeyemi Ogunbowale +6 more
wiley +1 more source
σ‐Decoupled C9 fluorene‐framework topology control enables narrowband red MR emitters. SF‐BNO and PF‐BNO share the same BNO core, but differ in closed/open fluorene ring closure. SF‐BNO improves steric shielding and stability, while PF‐BNO enhances PLQY, orientation, and efficiency. Ex‐PSF and TE‐OLED architectures deliver ultra‐low efficiency roll‐off
Aradhya Rajput +7 more
wiley +2 more sources
cGMP Signaling in Arterioles Revealed by FRET‐Based Real‐Time Measurement in Mice In Vivo
ABSTRACT cGMP evokes arteriolar vasorelaxation and is generated in smooth muscle by the soluble guanylyl cyclase (sGC) stimulated by endothelial NO. Phosphodiesterases (PDEs) degrade cGMP and may contribute in diameter regulation. We examined arteriolar cGMP levels in real‐time in vivo upon NO and acetylcholine (ACh) and effects of PDE inhibition ...
Lukas Thiele +6 more
wiley +1 more source
Theoretical Design of All-Optical Universal Logic via Multistage FRET-STED Energy Cascades in Fluorescent Protein Nanoclusters. [PDF]
Rakos B.
europepmc +1 more source
In lignin peroxidase and versatile peroxidase, low FRET from buried Trp to heme promotes long‐range electron transfer (LRET) from substrate to heme. This efficient electron flow is facilitated by reduced FRET competition. This mechanism likely evolved to enable the effective degradation of bulky, high‐redox‐potential lignin that cannot reach the enzyme'
Yi Ren +6 more
wiley +1 more source

