Results 111 to 120 of about 12,080,229 (289)
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Lockwood Letter. (Toledo, Ohio), July 1991
, 2019 The Lockwood Letter is a newspaper published by the Toledo Women's Bar Association published in part to "promote and advance the position of and opportunities available to women attorneys" in the Toledo ...
Toledo Women's Bar Association
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Texas Pattern Jury Charges [PDF]
, 2018 Guide listing pattern jury charges to assist the bench and bar in preparing the court's charge in the state of Texas, including definitions, instructions, and questions needed to submit jury charges. Indexes to statutes and rules cited, cases cited, and
State Bar of Texas. Committee on Pattern Jury Charges.
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Polarity kinases that phosphorylate F-BAR protein Cdc15 have unique localization patterns during cytokinesis and contributions to preventing tip septation in Schizosaccharomyces pombe. [PDF]
MicroPubl Biol, 2023 Igarashi MG +3 more
europepmc +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Lockwood Letter. (Toledo, Ohio), April 1986
, 2019 The Lockwood Letter is a newspaper published by the Toledo Women's Bar Association published in part to "promote and advance the position of and opportunities available to women attorneys" in the Toledo ...
Toledo Women's Bar Association
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Multiple polarity kinases inhibit phase separation of F-BAR protein Cdc15 and antagonize cytokinetic ring assembly in fission yeast. [PDF]
Elife, 2023 Bhattacharjee R +7 more
europepmc +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Lockwood Letter. (Toledo, Ohio), Fall 1990
, 2019 The Lockwood Letter is a newspaper published by the Toledo Women's Bar Association published in part to "promote and advance the position of and opportunities available to women attorneys" in the Toledo ...
Toledo Women's Bar Association
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Coriolis effects and the thermal bar [PDF]
, 2002 A model for the thermal bar system in the rotating frame that includes unsteady inertia is formulated. Asymptotic solutions are found to the initial value problem in the frictionless, small bottom slope limit.
Farrow, D.E.
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