Mito-Nuclear Discordance and Species Boundaries in the Freshwater Fish Genus <i>Cyprinion</i> Revealed by Genome-Wide SNPs. [PDF]
Hashemzadeh Segherloo I +3 more
europepmc +1 more source
Versatile vector tools for efficient protein screening across multiple expression systems
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu +5 more
wiley +1 more source
Learning is a fundamental source of individuality. [PDF]
Manna R +5 more
europepmc +1 more source
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
Habitat Heterogeneity Drives Niche Partitioning and Morphological Divergence in Two Parapatric <i>Diploderma</i> Lizard Species. [PDF]
Wen Y +6 more
europepmc +1 more source
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
Gene Families, Structural and Functional Contexts Shape Protein Thermostability and Paralog Divergence in <i>Arabidopsis</i>. [PDF]
Cheng Y +8 more
europepmc +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Nonadditive gene expression and reduced homoeolog expression bias in an intraspecific hexaploid wheat hybrid. [PDF]
Ardaman A, Forgiarini C, Arunkumar R.
europepmc +1 more source
CroCoNet: a framework for the quantitative comparison of gene regulatory networks across species. [PDF]
Térmeg A +10 more
europepmc +1 more source

