Results 331 to 340 of about 15,544,554 (381)
Histone Deacetylase 6 Brain PET in Amyotrophic Lateral Sclerosis‐Frontotemporal Spectrum Disorder
ABSTRACT Objective [18F]EKZ‐001 is a positron emission tomography (PET) tracer targeting histone deacetylase 6 (HDAC6), an enzyme responsible for intracellular transport and clearance of misfolded proteins. HDAC6 modulation is a promising treatment strategy in neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS).
Greet Vanderlinden+15 more
wiley +1 more source
Satisfied and Secured-An Integration of Self-Determination Theory and Attachment Theory in the Environmental Domain. [PDF]
Bureau JF+7 more
europepmc +1 more source
Objective The study objective was to estimate the budget impact of funding a standardized education and exercise therapy program, Good Life with osteoArthritis in Denmark (GLA:D) for people with hip and knee osteoarthritis (OA) waiting for total joint replacement (TJR) consultation in a universal publicly insured health care system in Canada.
Darren R. Mazzei+4 more
wiley +1 more source
Investigating the content and correlates of undergraduate students' academic regrets. [PDF]
Ranellucci J.
europepmc +1 more source
Relationship Between Gout Flare States and Patient‐Reported Outcomes After Allopurinol Initiation
Objective Gout flares are the most important clinical feature of the disease. A hypothetical maximum flare occurrence in the preceding six months has been suggested to be no flares for a patient‐acceptable symptom state (PASS) and only one flare for low disease activity (LDA).
Lisa K. Stamp+6 more
wiley +1 more source
Personalized mHealth Intervention (StepAdd) for Increasing Physical Activity in Japanese Patients With Type 2 Diabetes: Secondary Analysis of Social Cognitive Theory Measurements of a Single-Arm Pilot Study. [PDF]
Waki K+4 more
europepmc +1 more source
Objective Posttraumatic osteoarthritis (PTOA) accounts for nearly 12% of osteoarthritis incidences and often occurs after anterior cruciate ligament (ACL) tear. Ensuring the uptake of preventive treatments for PTOA requires that investigators and clinicians understand factors influencing patients to seek preventive therapies.
Lily M. Waddell+10 more
wiley +1 more source
The Impact of Shape and Decoration on User Experience and Visual Attention in Anthropomorphic Robot Design. [PDF]
Song T.
europepmc +1 more source