Results 61 to 70 of about 831,238 (272)

Logic Meets Algebra: the Case of Regular Languages [PDF]

open access: yesLogical Methods in Computer Science, 2007
The study of finite automata and regular languages is a privileged meeting point of algebra and logic. Since the work of Buchi, regular languages have been classified according to their descriptive complexity, i.e.
Pascal Tesson, Denis Therien
doaj   +1 more source

Circulating tumor cells in metastatic breast cancer patients treated with immune checkpoint inhibitors – a biomarker analysis of the ALICE and ICON trials

open access: yesMolecular Oncology, EarlyView.
In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen   +13 more
wiley   +1 more source

Preservation of Strong Normalisation modulo permutations for the structural lambda-calculus [PDF]

open access: yesLogical Methods in Computer Science, 2012
Inspired by a recent graphical formalism for lambda-calculus based on linear logic technology, we introduce an untyped structural lambda-calculus, called lambda j, which combines actions at a distance with exponential rules decomposing the substitution ...
Beniamino Accattoli, Delia Kesner
doaj   +1 more source

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

open access: yesMolecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld   +7 more
wiley   +1 more source

Real-Time Model-Checking: Parameters everywhere [PDF]

open access: yesLogical Methods in Computer Science, 2007
In this paper, we study the model-checking and parameter synthesis problems of the logic TCTL over discrete-timed automata where parameters are allowed both in the model (timed automaton) and in the property (temporal formula). Our results are as follows.
Veronique Bruyere, Jean-Francois Raskin
doaj   +1 more source

Detection rate for ESR1 mutations is higher in circulating‐tumor‐cell‐derived genomic DNA than in paired plasma cell‐free DNA samples as revealed by ddPCR

open access: yesMolecular Oncology, EarlyView.
Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou   +11 more
wiley   +1 more source

Menopausal symptoms in breast cancer survivors on adjuvant endocrine therapy compared with those of menopausal women [PDF]

open access: yes
Objectives: To compare menopausal symptoms of breast cancer survivors on adjuvant endocrine therapy with those of menopausal women. Study design: In a retrospective nested case-control study menopausal symptoms were compared of breast cancer survivors in
Anserini, Paola   +7 more
core   +1 more source

A Condensation-Ordering Mechanism in Nanoparticle-Catalyzed Peptide Aggregation [PDF]

open access: yes, 2009
Nanoparticles introduced in living cells are capable of strongly promoting the aggregation of peptides and proteins. We use here molecular dynamics simulations to characterise in detail the process by which nanoparticle surfaces catalyse the self ...
A Aggeli   +62 more
core   +5 more sources

Behavioural equivalences for timed systems [PDF]

open access: yesLogical Methods in Computer Science, 2019
Timed transition systems are behavioural models that include an explicit treatment of time flow and are used to formalise the semantics of several foundational process calculi and automata. Despite their relevance, a general mathematical characterisation
Tomasz Brengos, Marco Peressotti
doaj   +1 more source

Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value

open access: yesMolecular Oncology, EarlyView.
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song   +13 more
wiley   +1 more source

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