Results 81 to 90 of about 831,238 (272)

An X-ray spectral survey of the disc of M31 with XMM-Newton [PDF]

, 2008
We present the results of a complete spectral survey of the X-ray point sources detected in five XMM-Newton observations along the major axis of M31 but avoiding the central bulge, aimed at establishing the population characteristics of X-ray sources in ...
Barnard, Barnard, C. Tonkin, Colbert, Condon, Dickey, Ford, Galleti, Giacconi, Grimm, Grimm, J. P. Osborne, Kaaret, Kilgard, Kodaira, Kong, Kong, L. Shaw Greening, Magnier, Massey, Monet, Moretti, Osborne, Pietsch, Predehl, R. Barnard, Rosati, Sabogal, Shirey, Shtykovskiy, Strüder, Supper, Supper, Trinchieri, Trudolyubov, Turner, U. Kolb, van Speybroeck, Walterbos, Williams   +39 more
core   +2 more sources

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

A spectrograph instrument concept for the Prime Focus Spectrograph (PFS) on Subaru Telescope

, 2012
We describe the conceptual design of the spectrograph opto-mechanical concept for the SuMIRe Prime Focus Spectrograph (PFS) being developed for the SUBARU telescope.
Barkhouser, Robert, Carr, Michael, Fèvre, Olivier Le, Gunn, James, Jaquet, Marc, Madec, Fabrice, Martin, Laurent, Mignant, David Le, Prieto, Eric, Smee, Stephen, Sugai, Hajime, Tamura, Naoyuki, Vives, Sébastien   +12 more
core   +1 more source

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

A Rational Deconstruction of Landin's SECD Machine with the J Operator [PDF]

Logical Methods in Computer Science, 2008
Landin's SECD machine was the first abstract machine for applicative expressions, i.e., functional programs. Landin's J operator was the first control operator for functional languages, and was specified by an extension of the SECD machine.
Olivier Danvy, Kevin Millikin
doaj   +1 more source

On Cayley graphs of algebraic structures [PDF]

arXiv, 2018
We present simple graph-theoretic characterizations of Cayley graphs for left-cancellative monoids, groups, left-quasigroups and quasigroups. We show that these characterizations are effective for the end-regular graphs of finite degree.
arxiv  

Enhanced discovery of bacterial laccase‐like multicopper oxidase through computer simulation and metagenomic analysis of industrial wastewater

FEBS Open Bio, EarlyView.
We obtained potential bacterial laccase‐like multicopper oxidase (LMCO) sequences through metagenomic sequencing. All sequences exhibited significant differences from known LMCOs in databases. To select the most promising candidates, we performed structure prediction and molecular docking using alphafold2, metal3d and rosetta.
Ting Cui, Ariel Kushmaro, Hana Barak, Anja Poehlein, Rolf Daniel, Hans‐Jürgen Mägert   +5 more
wiley   +1 more source

NICMOS Observations of Luminous and Ultraluminous Infrared Galaxies [PDF]

, 1999
HST NICMOS observations of a sample of 24 luminous (LIGs: L_(IR) [8-1000 microns] = 10^(11.0-11.99) L_sun) and ultraluminous (ULIGs: L_(IR) > 10^(12.0) L_sun) infrared galaxies are presented.
Evans, A. S.
core   +1 more source

Model Checking Vector Addition Systems with one zero-test [PDF]

Logical Methods in Computer Science, 2012
We design a variation of the Karp-Miller algorithm to compute, in a forward manner, a finite representation of the cover (i.e., the downward closure of the reachability set) of a vector addition system with one zero-test.
Rémi Bonnet, Alain FInkel, Jérôme Leroux, Marc Zeitoun   +3 more
doaj   +1 more source

Weak Lensing Probes of Modified Gravity

, 2008
We study the effect of modifications to General Relativity on large scale weak lensing observables. In particular, we consider three modified gravity scenarios: f(R) gravity, the DGP model, and TeVeS theory.
Fabian Schmidt, S. Dodelson
core   +1 more source