Abstract Purpose Breast cancer is a neoplastic disease with high prevalence among women. Radiotherapy is one of the principal treatment modalities for this disease, but it poses significant challenges. This study aimed to compare and evaluate the technical and dosimetric performance of conventional C‐arm linac systems and a new design, Halcyon, in the ...
Mustafa Çağlar+8 more
wiley +1 more source
We discuss constraint structure of extended theories of gravitation (also known as f(R) theories) in the vacuum selfdual formulation introduced in ref.
Bojowald M+10 more
core +2 more sources
Relationship of cognitive decline with glucocerebrosidase activity and amyloid‐beta 42 in DLB and PD
Abstract Objective Dementia with Lewy bodies (DLB) and Parkinson's disease (PD) share clinical, pathological, and genetic risk factors, including GBA1 and APOEε4 mutations. Biomarkers associated with the pathways of these mutations, such as glucocerebrosidase enzyme (GCase) activity and amyloid‐beta 42 (Aβ42) levels, may hold potential as predictive ...
Maria Camila Gonzalez+15 more
wiley +1 more source
Phase 1, First‐In‐Human, Single‐/Multiple‐Ascending Dose Study of Iluzanebart in Healthy Volunteers
ABSTRACT Objective To evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of iluzanebart, a fully human monoclonal antibody TREM2 (triggering receptor expressed on myeloid cells 2) agonist, after single‐ (SAD) and multiple‐ascending‐dose (MAD) administration.
Andreas Meier+8 more
wiley +1 more source
Linear algorithm for solution n-Queens Completion problem [PDF]
A linear algorithm is described for solving the n-Queens Completion problem for an arbitrary composition of k queens, consistently distributed on a chessboard of size n x n. Two important rules are used in the algorithm: a) the rule of sequential risk elimination for the entire system as a whole; b) the rule of formation of minimal damage in the given ...
arxiv
Bulk viscous corrections to screening and damping in the deconfined phase at high temperature
Non-equilibrium corrections in a hot QCD medium modify the "hard thermal loops" (HTL) which determine the resummed propagators for gluons with soft momenta as well as the Debye screening and Landau damping mass scales.
Dumitru, Adrian
core +1 more source
CNS Mitochondria‐Derived Vesicle in Blood: Potential Biomarkers for Brain Mitochondria Dysfunction
ABSTRACT Objective Mitochondrial dysfunction is a hallmark of neurodegenerative diseases like Alzheimer's (AD) and Parkinson's (PD). Our goal was to develop practical, noninvasive methods to assess mitochondrial status through the detection of mitochondria‐derived vesicles (MDVs).
Qi Liu+12 more
wiley +1 more source
Histone Deacetylase 6 Brain PET in Amyotrophic Lateral Sclerosis‐Frontotemporal Spectrum Disorder
ABSTRACT Objective [18F]EKZ‐001 is a positron emission tomography (PET) tracer targeting histone deacetylase 6 (HDAC6), an enzyme responsible for intracellular transport and clearance of misfolded proteins. HDAC6 modulation is a promising treatment strategy in neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS).
Greet Vanderlinden+15 more
wiley +1 more source
Relationship Between Gout Flare States and Patient‐Reported Outcomes After Allopurinol Initiation
Objective Gout flares are the most important clinical feature of the disease. A hypothetical maximum flare occurrence in the preceding six months has been suggested to be no flares for a patient‐acceptable symptom state (PASS) and only one flare for low disease activity (LDA).
Lisa K. Stamp+6 more
wiley +1 more source
Renormalization of Schr\"odinger Equation and Wave Functional for Rapidly Oscillating Fields in QCD
Background field method is used to perform renormalization group transformations for Schr\"odinger equation in QCD. The dependence of the ground state wave functional on rapidly oscillating fields is found.Comment: 8pp ...
Floreanini R.+3 more
core +1 more source