Results 101 to 110 of about 663,881 (275)

Histone Deacetylase 6 Brain PET in Amyotrophic Lateral Sclerosis‐Frontotemporal Spectrum Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective [18F]EKZ‐001 is a positron emission tomography (PET) tracer targeting histone deacetylase 6 (HDAC6), an enzyme responsible for intracellular transport and clearance of misfolded proteins. HDAC6 modulation is a promising treatment strategy in neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS).
Greet Vanderlinden, Charles Carron, Donatienne Van Weehaeghe, Joke De Vocht, Fouke Ombelet, Pegah Masrori, Caro De Weerdt, Rebecca E. James, Lauren T. Evans, Frederick A. Schroeder, Jacob M. Hooker, Michel Koole, Janice E. Kranz, Tonya M. Gilbert, Philip Van Damme, Koen Van Laere   +15 more
wiley   +1 more source

Reproduction of Varroa destructor in sealed worker bee brood cells of Apis mellifera carnica and Apis mellifera syriaca in Jordan [PDF]

, 2008
The reproduction of the honey bee mite, Varroa destructor in sealed worker bee brood cells represents an important factor for the population development of this parasite in honey bee colonies.
Alattal, Yehya, Rosenkranz, Peter, Zebitz, Claus Paul Walter   +2 more
core  

Effect of fluoride concentration in pH 4.3 and pH 7.0 supersaturated solutions on the crystal growth of hydroxyapatite

Restorative Dentistry & Endodontics, 2012
Objectives Present study was undertaken to investigate the crystal growth onto synthetic hydroxyapatite (HA) seeds in pH 4.3 and pH 7.0 supersaturated solutions with different fluoride concentrations. Materials and Methods 8 groups of pH 4.3 and 7.0
Haneol Shin, Sung-Ho Park, Jeong-Won Park, Chan-Young Lee   +3 more
doaj   +1 more source

Estimating Budget Impact and Joint Replacement Avoidance by Implementing a Standardized Education and Exercise Therapy Program for Hip and Knee Osteoarthritis in a Publicly Insured Health Care System

Arthritis Care &Research, EarlyView.
Objective The study objective was to estimate the budget impact of funding a standardized education and exercise therapy program, Good Life with osteoArthritis in Denmark (GLA:D) for people with hip and knee osteoarthritis (OA) waiting for total joint replacement (TJR) consultation in a universal publicly insured health care system in Canada.
Darren R. Mazzei, Jackie L. Whittaker, Peter Faris, Tracy Wasylak, Deborah A. Marshall   +4 more
wiley   +1 more source

Two‐Year Follow‐Up of a Multidisciplinary Lifestyle Intervention for Rheumatoid Arthritis and Osteoarthritis

Arthritis Care &Research, Accepted Article.
Objective The Plants for Joints intervention (PFJ), including a whole‐food plant‐based diet, exercise, and stress reduction, reduced signs and symptoms of rheumatoid arthritis (RA) or metabolic syndrome‐associated hip or knee osteoarthritis (MSOA) compared to usual care. This study examined outcomes two years later. Methods After two 16‐week randomized
Carlijn A. Wagenaar, Wendy Walrabenstein, Marike van der Leeden, Franktien Turkstra, Martijn Gerritsen, Jos W.R. Twisk, Maarten Boers, Martin van der Esch, Henriët van Middendorp, Peter J.M. Weijs, Dirkjan van Schaardenburg   +10 more
wiley   +1 more source

Random Learning Leads to Faster Convergence in ‘Model‐Free’ ILC: With Application to MIMO Feedforward in Industrial Printing

International Journal of Adaptive Control and Signal Processing, EarlyView.
The cost as a function of the number of experiments for a non‐symmetric 21×21$$ 21\times 21 $$ system. Four approaches are shown: the proposed stochastic conjugate gradient ILC (SCGILC) method (), deterministic conjugate gradient ILC (), stochastic gradient descent ILC () and deterministic gradient descent ILC ().
Leontine Aarnoudse, Tom Oomen
wiley   +1 more source

Anomaly Detection Method for Hybrid Workpieces Using Dynamic Time Warping

Advanced Engineering Materials, EarlyView.
Monitoring of hybrid workpieces: when machining hybrid workpieces, unavoidable axial deviations of the material transition zone cause temporal shifts in the process force signals. A new anomaly detection method based on dynamic time warping is proposed to detect material defects.
Berend Denkena, Benjamin Bergmann, Heinrich Klemme, Miriam Handrup   +3 more
wiley   +1 more source

A Novel Approach on Rapid Alloy Development of Tool Steels for Laser Powder Bed Fusion by In Situ Alloying

Advanced Engineering Materials, EarlyView.
A novel approach for alloy development in laser powder bed fusion is introduced. Instead of producing massive samples of one composition at a time, prepressed powder bed samples produced from powder mixtures are processed. Guidelines for the selection of precursor powders are developed.
Felix Großwendt, Anna Strauch, Jonathan Lentz, Arne Röttger, Rainer Fechte‐Heinen, Sebastian Weber, Werner Theisen   +6 more
wiley   +1 more source

Effect of clay amendments on nitrogen leaching and forms in a sandy soil [PDF]

, 2010
Nitrogen (N) leaching in sandy soil decreases fertiliser use efficiency and may depress plant production. Application of high cation exchange capacity (CEC) materials (e.g.
Bell, R.W., Limpinuntana, V., Sitthaphanit, S.   +2 more
core   +1 more source

Nanoparticle‐Coated X2CrNiMo17‐12‐2 Powder for Additive Manufacturing – Part I: Surface, Flowability, and Optical Properties of SiC, Si, and Si3N4 Coated Metal Powders

Advanced Engineering Materials, EarlyView.
Herein, silicon‐based nanoparticle coatings on X2CrNiMo17‐12‐2 metal powder are presented. The coating process scale, process parameters, nanoparticle size (65–200 nm) as well as the coating amount are discussed regarding powder properties. The surface roughness affects the flowability, while reflectance depends on the coating material and surface ...
Arne Lüddecke, Nick Hantke, Harald Zetzener, Jan T. Sehrt, Arno Kwade   +4 more
wiley   +1 more source