Results 271 to 280 of about 3,494,638 (328)
TRIM40 Drives Pathological Cardiac Hypertrophy and Heart Failure via Ubiquitination of PKN2
This study identifies the E3 ligase TRIM40 as a key driver of pathological cardiac hypertrophy. TRIM40 binds PKN2 via its B‐box domain and, through its C29‐dependent catalytic activity, mediates K63‐linked ubiquitination of PKN2. This modification enhances PKN2 phosphorylation at Ser815, thereby driving hypertrophy.
Risheng Zhao +12 more
wiley +1 more source
Evaluating the performance of a generative AI model in assessing qualitative health research articles adherence to objective reporting standards. [PDF]
Chia AW, Teo WL, Munro YL, Dalan R.
europepmc +1 more source
F1 Scores for the GPT, Cohere, Llama, and Gemini LLMs on individual binarized PHQ-8 items.
Bazen Gashaw Teferra (21799468) +14 more
openalex +1 more source
Functional compensation between clarin‐1 and clarin‐2 in cochlear hair cells. Hearing loss associated with CLRN1 mutations shows striking phenotypic variability; however, the underlying mechanisms remain poorly understood. This study reveals that clarin‐1 and clarin‐2 function cooperatively in cochlear hair cells to sustain mechanoelectrical ...
Maureen Wentling +17 more
wiley +1 more source
Ensemble Deep Learning for Real-Bogus Classification with Sky Survey Images. [PDF]
Prommool P +3 more
europepmc +1 more source
A neural network‐enabled permittivity engineering paradigm is introduced, transcending traditional trial‐and‐error design. By decoupling electromagnetic parameters and screening a high‐throughput feature space, an ultrathin (1.0 mm) magnetic absorber is inversely designed, experimentally achieving a superior and customizable 5.1 GHz bandwidth and ...
Chenxi Liu +9 more
wiley +1 more source
Semantic code clone detection using hybrid intermediate representations and BiLSTM networks. [PDF]
Shahbaz Ismail M, Shahzad S, Quradaa FH.
europepmc +1 more source

