Results 61 to 70 of about 62,236 (88)

Abstract 3799: Regulation of p16-E2F1-CDK4/6 signaling by TRUC-16 ultraconserved long non-coding RNA

Cancer Research, 2023
High phylogenetic conservation of genomic loci is a potential marker of essential biological functionality. Ultraconserved elements (UCEs) are DNA sequences entirely conserved through millions of years of evolution, but their functions are not well ...
L. Fabris   +7 more
semanticscholar   +1 more source

Abstract 3799: Heparan sulfate modifiers and signaling between tumor-associated macrophages and cancer-associated fibroblasts in a biomimetic hydrogel model of bone-metastatic prostate cancer

Immunology, 2018
The establishment of a new tumor niche for most carcinomas is orchestrated primarily by the bidirectional engagement of cancer cells and fibroblasts.
Fabio Henrique Brasil da Costa   +3 more
semanticscholar   +1 more source

Augmenting Type 1 interferon antitumoral immune signaling in triple-negative breast cancer (TNBC) via combined radiotherapy and monopolar spindle kinase I (Mps1) inhibition 3799

Journal of Immunology
Triple-negative breast cancer (TNBC) exhibits inferior durable response to radiation treatment (RT) and worse locoregional and distant control, leading to poor clinical outcomes.
Kassidy M. Jungles   +6 more
semanticscholar   +1 more source

Abstract 3799: CDKN2ALow cancer cells outcompete macrophages for microenvironmental zinc to drive immunotherapy resistance

Cancer Research
Approximately 50% of cancers exhibit decreased CDKN2A expression (CDKN2ALow), which is linked to resistance to immune checkpoint blockade (ICB). The mechanisms driving ICB resistance due to CDKN2A loss alone remain largely unexplored.
R. Buj, K. Aird
semanticscholar   +1 more source

The fast transient AT 2023clx in the nearby LINER galaxy NGC 3799 as a tidal disruption of a very low-mass star

Astronomy & Astrophysics
We present an extensive analysis of the optical and ultraviolet (UV) properties of AT 2023clx, the closest optical/UV tidal disruption event (TDE) to date ($z=0.01107$), which occurred in the nucleus of the interacting low-ionization nuclear emission ...
P. Charalampopoulos   +32 more
semanticscholar   +1 more source

Abstract 3799: Spatial biomarker prediction in papillary renal cell carcinoma using artificial intelligence-based immunofluorescent inference

Cancer Research
Papillary renal cell carcinoma (pRCC) accounts for ~15-20% of the global burden for kidney cancers but still lacks effective mechanisms to predict patient responses to therapeutic intervention.
Jared Brewer   +3 more
semanticscholar   +1 more source

Routine Cerebral Embolic Protection during Transcatheter Aortic-Valve Implantation.

New England Journal of Medicine
BACKGROUND Transcatheter aortic-valve implantation (TAVI) is associated with procedure-related stroke. Cerebral embolic protection (CEP) devices may reduce embolization to the cerebral circulation and hence the incidence of stroke. METHODS We conducted
Rajesh K. Kharbanda   +45 more
semanticscholar   +1 more source

Cu interconnect lifetime estimation in the presence of thermal gradients

Journal of Applied Physics
Through physical and electrical analysis, the impact of thermal gradients on mass transport in Cu interconnects is studied using a dedicated test structure.
Y. Ding   +8 more
semanticscholar   +1 more source

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