Results 41 to 50 of about 33,743 (177)

Polyfluoroalkyl‐Tagged Cell‐Penetrating Peptide‐Additives Enhance Intracellular Protein Delivery via Sustained Monomeric Lipid Interaction

Angewandte Chemie International Edition, EarlyView.
We introduce cell‐penetrating peptides (CPPs) with polyfluoroalkyl‐tags that drastically enhance intracellular protein delivery by promoting membrane retention. Via the combination of live‐cell imaging, biophysical analysis, and computational simulations, we reveal how fluorous CPPs interact with membranes via monomeric interactions and dynamic tag ...
Sarah Hansen, Hana Zupan, Ferhat Mutlu, Jan Vincent V. Arafiles, Rubén Cruz, Palina Dubatouka, Kenichi Ataka, Martin Lehmann, Bettina G. Keller, Joachim Heberle, Christian P. R. Hackenberger   +10 more
wiley   +1 more source

México y el TLCAN: escenarios de política comercial. Simulaciones con un modelo de equilibrio general aplicado

El Trimestre Económico, 2018
Antecedentes: El desempeño de la estructura de la economía mexicana, especialmente la de su sector manufacturero, es muy dependiente del mercado norteamericano. Las dificultades del proceso de renegociación del Tratado de Libre Comercio de
Alejandro Dávila Flores, Horacio Enrique Sobarzo Fimbres, Miriam Valdés Ibarra   +2 more
doaj   +1 more source

Implementation of on-site velocity boundary conditions for D3Q19 lattice Boltzmann

, 2010
On-site boundary conditions are often desired for lattice Boltzmann simulations of fluid flow in complex geometries such as porous media or microfluidic devices.
Flekkøy E G, Frisch U, Halliday I, Harting J, Higuera F J, Hänel D, Jens Harting, Karniadakis G, Martin Hecht, Mattila K, Qian Y H, Schiller U D, Succi S, Sukop M C, Wieghardt K   +14 more
core   +1 more source

The volumetric rate of calcium-rich transients in the local universe [PDF]

, 2018
We present a measurement of the volumetric rate of `calcium-rich' optical transients in the local universe, using a sample of three events from the Palomar Transient Factory (PTF).
Frohmaier, C., Maguire, K., Nugent, P. E., Sullivan, M.   +3 more
core   +3 more sources

Capture of adeno‐associated viruses from clarified lysate by continuous flow ultracentrifugation: a comparative study of iodixanol and sucrose gradients

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Adeno‐Associated Virus vectors are widely used in gene therapy due to their safety and efficacy. Despite the interest in their therapeutical application, AAV purification remains a significant challenge. Density gradient ultracentrifugation using cesium chloride, sucrose, or iodixanol gradients are common methods for AAV ...
Sabrina Leigheb, Maral Rahimzadeh, Nikolaus Virgolini, Aida Tleuova, Mahbod Mousavian, Astrid Dürauer, Patricia Pereira Aguilar   +6 more
wiley   +1 more source

Activity of a novel antimicrobial peptide against Pseudomonas aeruginosa biofilms

Scientific Reports, 2018
With the increasing recognition of biofilms in human disease, the development of novel antimicrobial therapies is of critical importance. For example, in patients with cystic fibrosis (CF), the acquisition of host-adapted, chronic Pseudomonas aeruginosa ...
Trevor Beaudoin, Tracy A. Stone, Miroslawa Glibowicka, Christina Adams, Yvonne Yau, Saumel Ahmadi, Christine E. Bear, Hartmut Grasemann, Valerie Waters, Charles M. Deber   +9 more
doaj   +1 more source

Characterization of virulence genes in Escherichia coli strains isolated from pre-weaned calves in the Republic of Korea

Acta Veterinaria Scandinavica, 2020
Background Escherichia coli is an important cause of diarrhea in calves and its diarrheagenic properties are related to presence of certain virulence genes. In this study, the prevalence of virulence genes F5, F17, F41, sta, stx1, stx2, eae, and saa in E.
Ji-Hyoung Ryu, SuHee Kim, Jinho Park, Kyoung-Seong Choi   +3 more
doaj   +1 more source

Fluorinated or brominated meta‐diamides as the new scaffolds for the treatment of rice bacterial leaf blight

Food and Energy Security, 2023
Rice is the main calorie source and stable food for half of the global population worldwide, while the rice bacterial leaf blight has been one of the main challenges to rice yields and quality.
Shengxin Guo, Feng He, Wei Zhang, Ya Wang, Lijiao Yu, Jian Wu   +5 more
doaj   +1 more source

Discriminating Local Sources of High-Energy Cosmic Electrons and Positrons by Current and Future Anisotropy Measurements

, 2018
The Fermi-LAT detects no significant anisotropy of the cosmic-ray (CR) electrons and positrons ($e^-+e^+$) with seven years of data, which provides the strongest restriction to the $e^-+e^+$ anisotropy up to now.
Bi, Xiao-Jun, Fang, Kun, Yin, Peng-fei
core   +1 more source

Susceptibility of Phthorimaea absoluta (Meyrick) (Lepidoptera: Gelechiidae) to novel and established insecticides in Brazil: resistance survey, baseline, and implications for management

Pest Management Science, EarlyView.
Baseline susceptibility of Phthorimaea absoluta to novel insecticides isocycloseram and tolfenpyrad was established in Brazil. Diagnostic doses were proposed for early resistance detection. Early tolfenpyrad tolerance and abamectin‐driven cross‐tolerance to isocycloseram via oxidases highlight cross‐resistance risks, emphasizing the need for routine ...
Vitor Quintela, Teófilo P Langa, José VCR Dantas, Marcos de Oliveira, Herbert AA Siqueira   +4 more
wiley   +1 more source