Results 41 to 50 of about 8,261 (198)

México y el TLCAN: escenarios de política comercial. Simulaciones con un modelo de equilibrio general aplicado

El Trimestre Económico, 2018
Antecedentes: El desempeño de la estructura de la economía mexicana, especialmente la de su sector manufacturero, es muy dependiente del mercado norteamericano. Las dificultades del proceso de renegociación del Tratado de Libre Comercio de
Alejandro Dávila Flores, Horacio Enrique Sobarzo Fimbres, Miriam Valdés Ibarra   +2 more
doaj   +1 more source

A Modular Mechanistic In Silico Model for In Vitro Transcription Process Yield and Product Quality Prediction

Biotechnology and Bioengineering, EarlyView.
ABSTRACT In vitro transcription (IVT) plays a critical role in the manufacture of mRNA vaccines and therapeutics. Optimizing mRNA yield and ensuring product quality, such as capping efficiency and integrity, are essential but mechanistically complex. This study presents a modular mechanistic model of the IVT process to advance scientific understanding ...
Keqi Wang, Keilung Choy, Eli Reiser, Jinxiang Pei, Hua Zheng, Aparajita Dasgupta, Fuqiang Cheng, Guogang Dong, Bhanu Chandra Mulukutla, Joshua Mannheimer, Carolyn Huang, Hooman Farsani, Wei Xie   +12 more
wiley   +1 more source

Constant Voltage Iontophoresis Technique to Deliver Terbinafine via Transungual Delivery System: Formulation Optimization Using Box–Behnken Design and In Vitro Evaluation

Pharmaceutics, 2021
Topical therapy of antifungals is primarily restricted due to the low innate transport of drugs through the thick multi-layered keratinized nail plate. The objective of this investigation was to develop a gel formulation, and to optimize and evaluate the
Anroop B. Nair, Bandar E. Al-Dhubiab, Jigar Shah, Bapi Gorain, Shery Jacob, Mahesh Attimarad, Nagaraja Sreeharsha, Katharigatta N. Venugopala, Mohamed A. Morsy   +8 more
doaj   +1 more source

Laryngeal Dysfunction Following COVID‐19: A TriNetX Retrospective Cohort Study

The Laryngoscope, EarlyView.
COVID‐19 is associated with an increased incidence of new‐onset laryngeal dysfunction, including chronic cough, dysphagia, voice disorders, vocal fold paralysis, and laryngeal spasm, compared with uninfected controls. Risk peaks one to two years after infection for most outcomes and is influenced by factors such as hospitalization, mechanical ...
Cali Loblundo, Warren B. Chun, Shaun A. Nguyen, Kirsten Meenan, Ashli K. O'Rourke   +4 more
wiley   +1 more source

Progressive prosecution in context: Examining the impact of prosecutorial administration change on case‐processing patterns and racial disparities

Criminology &Public Policy, EarlyView.
Abstract Research Summary Using administrative case‐processing records and interviews with prosecutors, we examine how a change in prosecutorial administration impacts charging and plea‐bargaining practices and racial and ethnic disparities in two jurisdictions led by progressive prosecutors who replaced more traditional administrations.
Rachel Bowman, Belén Lowrey‐Kinberg, Jon B. Gould   +2 more
wiley   +1 more source

Table_4_Insights Into Long Non-Coding RNA and mRNA Expression in the Jejunum of Lambs Challenged With Escherichia coli F17.XLSX

, 2022
It has long been recognized that enterotoxigenic Escherichia coli (ETEC) is the major pathogen responsible for vomiting and diarrhea. E. coli F17, a main subtype of ETEC, is characterized by high morbidity and mortality in young livestock.
Ziming Ren (9983183), Joram M. Mwacharo (7875956), Xiaoyang Lv (3154962), Weibo Zhang (5027921), Tingyan Hu (12403231), Wei Sun (93580), Weihao Chen (431221), Xiukai Cao (7287077), Tesfaye Getachew (4391326), Aynalem Haile (4391323)   +9 more
core   +1 more source

The Impact of Hard Brexit on Polish Exports

International Journal of Management and Economics, 2018
The decision of the United Kingdom (UK) to leave the European Union (EU) is unprecedented, especially considering the recent trend in the global economy toward economic integration. There is a multitude of research concerning the implications of economic
Borowski Jakub, Olipra Jakub, Błaszyński Paweł   +2 more
doaj   +1 more source

Characterization of virulence genes in Escherichia coli strains isolated from pre-weaned calves in the Republic of Korea

Acta Veterinaria Scandinavica, 2020
Background Escherichia coli is an important cause of diarrhea in calves and its diarrheagenic properties are related to presence of certain virulence genes. In this study, the prevalence of virulence genes F5, F17, F41, sta, stx1, stx2, eae, and saa in E.
Ji-Hyoung Ryu, SuHee Kim, Jinho Park, Kyoung-Seong Choi   +3 more
doaj   +1 more source

Elevated lymphoma risk in patients with chronic pruritus and chronic prurigo

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and objectives Chronic pruritus (CP) and chronic prurigo (CPG, including prurigo nodularis) are prevalent, debilitating diseases with diverse comorbidities, including malignancies. This retrospective cohort study evaluated the prevalence and risk of lymphoma in CP and CPG patients, including key risk factors, and sex‐ and ancestry ...
Svenja Royeck, Henning Olbrich, Steffen Koschmieder, Claudia Zeidler, Felix Witte, Konstantin Agelopoulos, Henning Wiegmann, Michael Storck, Johannes Benedict Oehm, Ralf J. Ludwig, Sonja Ständer   +10 more
wiley   +1 more source

Deep reinforcement learning for multi‐restart metaheuristics: an environment design for a hybrid of unbiased exploratory search and covariance matrix adaptation evolution strategy

International Transactions in Operational Research, EarlyView.
Abstract Multi‐restart metaheuristics can be highly effective for complex optimization problems, yet their performance depends critically on how restarts and algorithmic parameters are selected. This paper introduces a reinforcement learning approach for managing restart‐level decisions and parameter configurations in the UES–CMA‐ES hybrid ...
Antonio Bolufé‐Röhler, Bowen Xu
wiley   +1 more source