Results 21 to 30 of about 432 (114)

PROTAC‑Mediated HMGCR Depletion Reprograms Lipid Metabolism in Breast Cancer to Potentiate Photoimmunotherapy via Ferroptosis

Advanced Science, Volume 13, Issue 13, 3 March 2026.
This work introduces a study that identifies HMGCR as a novel target in TNBC and develops a light‐gated PROTAC nanomedicine. Upon irradiation, this agent selectively degrades HMGCR, reprogramming lipid metabolism to induce ferroptosis and potent antitumor immunity, thereby significantly enhancing photoimmunotherapy efficacy.
Tong Su, Guang Li, Yudong Guan, Qi Tian, Youzhi Qi, Yanqiu Zhang, Wenqian Wei, Xinxin Duan, Jiaxin Rui, Hongyan Zhu, Zengping Lin, Changchuan Xie, Zheni Xu, Yaying Wu, Xin Peng, Zhenjie Wang, Kun Chen, Xiaoyan Xin, Bing Zhang   +18 more
wiley   +1 more source

Regenerative Polyphenolic Free‐Standing Conductive Film

Macromolecular Materials and Engineering, Volume 311, Issue 2, February 2026.
A rare combination of self‐assembly, spontaneous regeneration, and free‐standing form is achieved from initially non‐conductive polyphenol–amine complexes. The resulting films, assembled at the air/water interface and carbonized in one step, demonstrate flexibility, conductivity, and scalability.
Jun Sung Kim, Jingxian Wu, Yunhan Lee, Mun Ja Kim, Haeshin Lee   +4 more
wiley   +1 more source

Comorbidities in People With Intellectual Disability With and Without Schizophrenia and Schizophrenia Without Intellectual Disability: A Swedish Register Study (IDcare)

Journal of Intellectual Disability Research, Volume 70, Issue 2, Page 206-217, February 2026.
ABSTRACT Background Intellectual disability (ID) and schizophrenia are known to separately carry a high risk of comorbidity of mental health and physical conditions. However, the prevalence and risk of comorbidities among people diagnosed with concurrent ID and schizophrenia have to date not been studied.
Trine Lise Bakken, Anna Axmon, Magnus Sandberg   +2 more
wiley   +1 more source

Assessment of morphological and molecular variation in local olive (Olea europaea L.) in the Northern part of Iran [PDF]

, 2016
Iran is known as one of the origins of olive in the world with many different olive cultivars, mainly in the north. Eighty eight accessions belong to 4 main olive cultivars were investigated by 21 morphological characters and 11 ISSR markers. Analyses of
Habibo allah Samizade Lahiji, Mahnaz Nezamivand Chegini, Mohammad Mohsenzadeh Golfazani, Mohammad Ramezani Malekroudi, Ramin Seighalani   +4 more
core   +3 more sources

Revisiting Ferroelectric‐Gated Phototransistors: A Tripartite Synapse‐Inspired Approach to In‐Sensor Image Processing

Advanced Materials, Volume 38, Issue 1, 2 January 2026.
A ferroelectric‐gated phototransistor (FGPT) enables linear and multilevel modulation of photoconductance through partial polarization switching and photogating effects. The device achieves photonic non‐volatility over a 153 dB dynamic range and performs in‐sensor processing under unstructured illumination, demonstrating enhanced face recognition ...
Yubin Lee, Dong Hyun Seo, Jun Seo Lee, Jae Min Jeon, Hyung Rae Kim, Min Seok Kim, Chaehyeon Ahn, Sung‐Un An, Jihun Choi, Hyunseung Kim, Chang Kyu Jeong, Hyunseob Lim, Dong‐Ho Kang, Young Min Song   +13 more
wiley   +1 more source

New biocontrol opportunities for prickly acacia: exploration in India [PDF]

, 2015
Prickly acacia (Vachellia nilotica ssp. indica), a multipurpose tree native to the Indian subcontinent, is a Weed of National Significance and is widespread throughout the grazing areas of northern Australia. Biological control of V. nilotica ssp. indica
Dhileepan, K.
core   +1 more source

Photothermal Hydrogel with Mn3O4 Nanoparticles Alleviates Intervertebral Disc Degeneration by Scavenging ROS and Regulating Extracellular Matrix Metabolism

Advanced Functional Materials, Volume 35, Issue 49, December 2, 2025.
The MPTT‐nanozyme‐hydrogel system (Mn3O4@ChS‐HA) provides a multifunctional therapeutic strategy for intervertebral disc degeneration (IVDD), effectively targeting oxidative stress and enhancing AF repair by restoring extracellular matrix (ECM) and redox homeostasis.
Yangyang Chen, Chan Xue, Feifei Ni, Binwu Hu, Miaoheng Yan, He Zhang, Yuxiang Hu, Xiaoyao Peng, Guangfang Li, Yu Han, Hongjian Liu, Zengwu Shao, Qin Wang, Yulong Wei   +13 more
wiley   +1 more source

Breeding Quality Protein Maize (QPM): Protocols for Developing QPM Cultivars [PDF]

This manual is intended for maize breeders who would like to start developing quality protein maize (QPM) cultivars. It is a compilation and consolidation of several breeding protocols successfully used at CIMMYT over two decades of QPM development and ...
Diallo, Alpha O., Krivanek, A.F., Palacios-Rojas, N., Twumasi-Afriyie, S., Vivek, B.S.   +4 more
core   +1 more source

Leveraging high‐dimensional seed colorspace in phenomic selection models for herbaceous perennial crops

The Plant Phenome Journal, Volume 8, Issue 1, December 2025.
Abstract Herbaceous perennial crops, which only recently entered the domestication pipeline, offer the potential of ecological benefits in agricultural systems but remain underdeveloped, partly due to slow breeding cycles. Early‐stage phenomic selection, the process of using high‐dimensional secondary traits to predict target traits, may accelerate ...
William Keaggy, Zachary N. Harris, Jackson Braley, Eric Cassetta, Jorge Gutierrez, Emelyn Piotter, Haley Schuhl, Jared L. Crain, Lee R. DeHaan, M. Kathryn Turner, Noah Fahlgren, Jenna Hershberger, Brandon Schlautman, David L. Van Tassel, Matthew J. Rubin, Allison J. Miller   +15 more
wiley   +1 more source

NMFS / Interagency Working Group Evaluation of CITES Criteria and Guidelines. [PDF]

, 2002
EXECUTIVE SUMMARY: At present, the Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES) criteria used to assess whether a population qualifies for inclusion in the CITES Appendices relate to (A) size of the population,
Bruckner, Andy W., Daves, Nancy K., Field, John D., Hunter, John R., Kohler, Nancy E., Kope, Robert G., Lieberman, Susan S., Mace, Pamela M., Miller, Margaret W., Orr, James W., Otto, Robert S., Smith, Tim D., Thompson, Nancy B.   +12 more
core