Antibacterial peptide PMAP-37(F34-R), expressed in Pichia pastoris, is effective against pathogenic bacteria and preserves plums [PDF]
Microbial Cell Factories, 2023 Background Recently, researchers have focused on the search for alternatives to conventional antibiotics. Antimicrobial peptides are small bioactive peptides that regulate immune activation and have antibacterial activity with a reduced risk of bacterial
Chunming Dong
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Enhancing the antibacterial activity of antimicrobial peptide PMAP-37(F34-R) by cholesterol modification [PDF]
BMC Veterinary Research, 2020 Background The problem of increasing resistance against conventional antibiotics has drawn people’s attention. Therefore, the development of novel antibacterial agents with effective and safe therapeutic effects is imminent. Antimicrobial peptides (AMPs)
Chengshui Liao, Chen Wang, Tengfei Shen
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Sex- and <i>APOE</i>-specific transcriptomic drug repurposing identifies four candidate therapeutics for Alzheimer's disease. [PDF]
Alzheimers Dement (N Y)Abstract Introduction Alzheimer's disease (AD) risk is strongly modified by biological sex and apolipoprotein E (APOE) genotype, yet these factors are rarely incorporated into drug discovery efforts. We hypothesized that sex‐ and APOE‐specific transcriptomic signatures define distinct molecular endotypes of AD which can be therapeutically targeted ...
Vitali F +6 more
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Application of Cell-Free DNA Barcode-Enabled Single-Molecule Test for Non-Invasive Prenatal Testing of α-Thalassemia and β-Thalassemia. [PDF]
J Clin Lab AnalWe evaluated the cfBEST assay for non‐invasive prenatal testing of α‐ and β‐thalassemia in 72 families. The assay correctly identified 88 of 93 fetal alleles, achieving an overall accuracy of 94.6%, a sensitivity of 94%, and a specificity of 95.35%, with 100% concordance with postnatal follow‐up.
Liu Q +7 more
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Leveraging serum CHI3L1 and machine learning for non-invasive liver fibrosis diagnostics [PDF]
iScienceSummary: This study was aimed to develop non-invasive liver fibrosis diagnostic model using chitinase 3-like protein 1 (CHI3L1) based on machine learning (ML).1,011 follow-up patients (556 training/455 validation) were enrolled, staging fibrosis via ...
Haizhen Chen +5 more
doaj +2 more sources
The Swedish National Quality Register for Repetitive Transcranial Magnetic Stimulation. [PDF]
Acta Psychiatr ScandABSTRACT Objective Repetitive transcranial magnetic stimulation (rTMS) has been demonstrated to be an effective and well tolerated treatment for depression, and it is being investigated also for other indications. This study presents the Swedish National Quality Register for rTMS (Q‐rTMS).
Hagsäter SM +6 more
europepmc +2 more sources
Management, 2021 This study investigates the relationship between FDI, economic growth and financial development in the Next 11 countries. An analysis of the results was performed accordingly on the panel data gathered from the Next 11 countries from 1985 to 2019— using ...
Louail Bilal, Zouita Mohamed Salah
doaj +1 more source
El Trimestre Económico, 2021 Este reporte constituye un informe preliminar que analiza la crisis y el endeudamiento de los países, en particular, aquellos en desarrollo y con mercados emergentes, frente a la pandemia de la Covid-19.
Commission on Global Economic Transformation (CGET)
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Determinants of the Trade Balance in India. Evidence from a Post-Liberalisation Period
Studia Universitatis Vasile Goldis Arad, Seria Stiinte Economice, 2022 The present study investigates trade balance determinants in post-liberalization India from 1991 to 2020. The main aim of this study is to test the validity of the J-curve and Marshal-Lerner condition and examine the impact of other related macroeconomic
Parray Waseem A. +2 more
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The short and long run effects of debt reduction: Evidence from debt relief under the enhanced HIPC and MDR initiatives [PDF]
Journal of Asian Business and Economic Studies, 2018 Purpose – The purpose of this paper is to estimate benefits to debt reduction by using the natural experiment provided by the debt relief programs: the Heavily Indebted Poor Countries Initiative launched by the International Monetary Fund and World Bank ...
Kelsey Gamel, Pham Hoang Van
doaj +1 more source