Physical Fitness in World-Class Shot Put Para Athletes During Six Months of Training: A Longitudinal Case Report [PDF]
The purpose of this longitudinal case report was to assess physical fitness changes in world-class shot put para athletes during six months of training. One male (age: 34.8 years; mass: 96.9 kg; height: 1.79 m; sport class: F42), and one female (age: 45 ...
Exal Garcia-Carrillo +8 more
doaj +3 more sources
Case Report: Jet lag and travel fatigue effects on performance in a world-class paralympic shot-putter after eastward long-haul transmeridian travel [PDF]
IntroductionThis case report aimed to examine the effects of long-haul eastward transmeridian travel on neuromuscular performance, subjective well-being, and internal training load in a World-class female Paralympic shot-putter preparing for the Paris ...
Exal Garcia-Carrillo +17 more
doaj +3 more sources
F54. PHARMACOLOGICAL ENHANCEMENT OF COGNITION AND SOCIAL COGNITION IN THE PSYCHOSIS SPECTRUM [PDF]
BACKGROUND: Abnormalities in cognition and social cognition represent a core feature of the schizophrenia spectrum disorders. Schizotypal personality disorder (SPD) is a milder disorder within the schizophrenia spectrum, characterized by attenuated, schizophrenia-like traits without overt psychosis.
Mercedes Perez-Rodriguez, M +6 more
openaire +2 more sources
Psychotropic Prescribing Patterns Among Bipolar-I Patients Prior to Established Bipolar-I Disorder Diagnosis. [PDF]
ABSTRACT Objective Bipolar I Disorder (BP‐I) is frequently misdiagnosed as Major Depressive Disorder (MDD), delaying appropriate treatment. This study aimed to examine treatment patterns among BP‐I patients misdiagnosed with MDD and assess the impact of these regimens on the time until BP‐I diagnosis.
Haile F, English C, Lee K.
europepmc +2 more sources
Sequence Properties of an Intramolecular Interaction that Inhibits p53 DNA Binding [PDF]
An intramolecular interaction between the p53 transactivation and DNA binding domains inhibits DNA binding. To study this autoinhibition, we used a fragment of p53, referred to as ND WT, containing the N-terminal transactivation domains (TAD1 and TAD2 ...
Emily Gregory, Gary W. Daughdrill
doaj +2 more sources
Contrasting Habitat Use at the Range Edge of an Endangered Grassland Specialist: Insights Into Plains-Wanderer (<i>Pedionomus torquatus</i>) Habitat Use in a Periphery Population. [PDF]
Habitat use at the range periphery of an endangered, Australian endemic bird was found to differ from key habitat described in the core range. Our study identifies the long‐held notion that Plains‐wanderers are exclusively ‘grassland specialists’ should be broadened to incorporate low forb‐like chenopod shrublands. Notably, despite these differences in
Gerhardy SP +3 more
europepmc +2 more sources
Blood Alcohol Concentration in Finnish Suicide Deaths and Associated Risk Factors, 2016-2024. [PDF]
ABSTRACT Aims There is limited research examining the relationship between blood alcohol concentration (BAC) and other risk factors among suicide deaths in Finland. Our study aimed to investigate the relationship of an elevated (more than zero) blood alcohol concentration with medical history, including sociodemographic characteristics and disease ...
Pokornyi T, Grainger M, Partonen T.
europepmc +2 more sources
Allelic polymorphism controls autoreactivity and vaccine elicitation of human broadly neutralizing antibodies against influenza virus. [PDF]
Summary Human broadly neutralizing antibodies (bnAbs) targeting the hemagglutinin stalk of group 1 influenza A viruses (IAVs) are biased for IGHV1-69 alleles that use phenylalanine (F54) but not leucine (L54) within their CDRH2 loops.
Sangesland M +12 more
europepmc +2 more sources
Naturally self-reactive B cells are poised to cross the selection barrier into autoimmune germinal centers. [PDF]
SUMMARY Roughly 20% of circulating B cells react with self-antigens. An open question is whether germline autoreactivities expand when immune tolerance is breached.
Yi-Dan Zhu D +16 more
europepmc +2 more sources

