Results 101 to 110 of about 50,649 (240)

An Extended Transcriptomic Landscape of Human Skin Mast Cells: Unveiling Lineage‐Specific Noncoding RNA Dynamics in FcεRI Activation

open access: yesAllergy, EarlyView.
FcεRI cross‐linking triggers widespread transcriptional reprogramming in human skin mast cells (> 5000 genes, > 6400 promoters, and 48 novel mast cell‐enriched lncRNAs). Breast skin and foreskin mast cells share core transcriptional programs but differ selectively in tryptase isoenzymes and IL‐8/IL‐1RA release.
Gürkan Bal   +12 more
wiley   +1 more source

Clinical and molecular features of PRCD‐associated retinopathy

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To describe the clinical and genetic characteristics of patients with biallelic disease‐causing variants in the PRCD (Progressive Rod‐Cone Degeneration) gene. Methods Multicentre, retrospective cohort study of 19 patients from 13 families across nine reference centres in six countries.
Vasil Kostin   +30 more
wiley   +1 more source

Platinum Group Element Traces of CAMP Volcanism Associated With Low‐Latitude Environmental and Biological Disruptions

open access: yesGeophysical Monograph Series, Page 263-304., 2021

Exploring the links between Large Igneous Provinces and dramatic environmental impact

An emerging consensus suggests that Large Igneous Provinces (LIPs) and Silicic LIPs (SLIPs) are a significant driver of dramatic global environmental and biological changes, including mass extinctions.
Jessica H. Whiteside   +3 more
wiley  

+1 more source

A genetic and historical perspective on the origins of keratitis fugax hereditaria

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To investigate the genetic and genealogical background of keratitis fugax hereditaria (KFH), a periodic corneal disease caused by the heterozygous pathogenic variant c.61G>C in the NLRP3 gene. KFH is characterized by recurrent unilateral autoinflammatory attacks alternating between the eyes and permanent corneal opacities.
Annamari T. Immonen   +7 more
wiley   +1 more source

Typical interaction between HAV with F6 Fab.

open access: yes, 2019
(A) The F6 footprints on the HAV surface. The figure shows a 2D projection of the HAV surface produced using RIVEM [25]. Residues of VP1, VP2, and VP3 are outlined in pale blue, green, and purple, respectively; residues involved in binding to F6 are ...
Ling Zhu (56356)   +10 more
core   +1 more source

Revisiting Ferritin‐IgG Score to Predict Complete Biochemical Response in Autoimmune Hepatitis

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
The ferritin‐IgG score failed external validation in a large Spanish multicentre cohort. However, baseline IgG ≥ 1.89×ULN independently predicted both complete biochemical response and biochemical response (defined as transaminase normalization), identifying patients less likely to achieve timely remission with standard therapy.
Álvaro Díaz‐González   +20 more
wiley   +1 more source

Aqueous Extracts of Rhus trilobata Inhibit the Lipopolysaccharide-Induced Inflammatory Response In Vitro and In Vivo

open access: yesPlants
Chronic noncommunicable diseases (NCDs) are responsible for approximately 74% of deaths globally. Medicinal plants have traditionally been used to treat NCDs, including diabetes, cancer, and rheumatic diseases, and are a source of anti-inflammatory ...
Alejandra Jazmín Rodríguez-Castillo   +9 more
doaj   +1 more source

Formulated imatinib mesylate floating sustained-release tablet F6 (B), and swelled tablet after 24 hours (A) in 0.1 N HCl.

open access: yes, 2015
Formulated imatinib mesylate floating sustained-release tablet F6 (B), and swelled tablet after 24 hours (A) in 0.1 N HCl.
Ali Kadivar (748591)   +7 more
core   +1 more source

Welcome to the jangle (fallacy): The case of statistics and mathematics anxieties

open access: yesBritish Journal of Educational Psychology, EarlyView.
Abstract Background Statistics‐related anxiety is a common barrier to learning in higher education, particularly for psychology and other non‐specialist students. High prevalence rates are concerning because statistical literacy is integral to academic success, employability and informed citizenship.
Jenny Terry, Charlie Lea, Andy P. Field
wiley   +1 more source

Development and evaluation of artificial intelligence literacy training for teacher education students

open access: yesBritish Journal of Educational Technology, EarlyView.
Abstract Teacher education students play double role as present learners and future educators. Hence, they need targeted training to navigate the growing influence of Generative Artificial Intelligence (GenAI) on teaching, learning and professional identity.
Tam Hong Le   +5 more
wiley   +1 more source

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