Results 191 to 200 of about 50,649 (240)

A Scalable, Traceable Computational‐to‐Experimental Pipeline for Activity‐Guided Identification of Bioactive Constituents: A Case Study in Salvia miltiorrhiza Bunge

open access: yesChemistry &Biodiversity, Volume 23, Issue 11, November 2026.
A scalable, traceable workflow integrating network pharmacology, activity‐guided separation, spectrum–effect analysis, and molecular simulation identifies cryptotanshinone as a major anti–Parkinson's disease constituent of Salvia miltiorrhiza. Its neuroprotective activity is linked to stable MAO‐B interactions, restoration of ATP levels, and enhanced ...
Xin Wang   +5 more
wiley   +1 more source

Utility of Fine Needle Aspiration Supernatant for Real‐Time PCR–Based Mutation Analysis in Non–Small Cell Lung Cancer

open access: yesDiagnostic Cytopathology, Volume 54, Issue 11, Page 805-811, November 2026.
ABSTRACT Background The emergence of personalized therapy and molecular sequencing has significantly transformed the management of advanced non–small cell lung carcinoma (NSCLC). Supernatants obtained from fine needle aspiration (FNA) have been shown to be a reliable source of high‐quality nucleic acid for molecular testing.
Adeyinka Akinsanya   +9 more
wiley   +1 more source

Supercritical Fluid Chromatography for Expedited Sample Clean‐Up in Isotope Ratio Mass Spectrometry Including Cholesterol as New Endogenous Reference Compound

open access: yesDrug Testing and Analysis, Volume 18, Issue 11, Page 1509-1522, November 2026.
Supercritical fluid chromatography was employed in the sample preparation for IRMS determinations in sports drug testing for the first time and the developed method was successfully validated. Cholesterol (CHOL) was introduced as a novel endogenous reference compound and population‐based Δ‐values were established as shown here.
Thomas Piper, Jana Drewes, Mario Thevis
wiley   +1 more source

Proteomic Profiling and Targeted Validation Reveal a More Extensive Salivary than Serum Response to a Feed-Deprivation Protocol in Horses with Gastric Lesions. [PDF]

open access: yesAnimals (Basel)
Matas-Quintanilla M   +6 more
europepmc   +1 more source

Event‐Related Potential Components and the Lexical Decision Task in Greek‐Speaking Children With and Without Reading Difficulties

open access: yesDyslexia, Volume 32, Issue 4, November 2026.
ABSTRACT The present study examined neurocognitive differences in visual word processing between children with reading difficulties (RD) and chronological‐age‐matched controls (CA) using event‐related potentials (ERPs) during a lexical decision task. Participants were Grade 3 and Grade 6 children (ages 7.6–12.1 years) who were required to discriminate ...
A. Fella   +2 more
wiley   +1 more source

Serpin A1 Cargo Within Tumour‐Derived Extracellular Vesicles Supports Pro‐Tumoural Bias of Neutrophils in Cancer

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 11, November 2026.
ABSTRACT Tumour‐derived extracellular vesicles (EVs) or exosomes are critical mediators of the cancer‐immune system crosstalk, yet the mechanisms by which they reprogram neutrophil function in vivo remain insufficiently characterised. Here, we identify the serine protease inhibitor Serpin A1 as a predominant cargo component of small EVs (sEVs) released
Maksim Domnich   +22 more
wiley   +1 more source

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