Results 201 to 210 of about 34,321,194 (310)

Response dynamics of discrete subiculum→retrosplenial cortex projections underlying trace fear conditioning. [PDF]

iScience
Bassett TE, Wang YZ, Wood EM, Zhang H, Petrovic Z, Prifti V, Jovasevic V, Yamawaki N, Ren L, Khalatyan N, Grayson V, Savas JN, Radulovic J, Cicvaric A.   +13 more
europepmc   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Evaluation of Shear Performance of Integrated GFRP Stirrup Systems in Reinforced Concrete Beams. [PDF]

Polymers (Basel)
Kartal S, Gündoğan U, Kalkan İ, Alahmari TS, Lakhouit A, Duvan A.   +5 more
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

French-Canadian adaptation and validation of the adolescents' Pain Coping Questionnaire. [PDF]

Can J Pain
Théroux J, Lessard L, Innes S, Gardner J, Gilbert G, Genest C, St-Arneault K, Carmel J, Cara-Slavich S, Larue C, Parent S, Barchi S, Turgeon I, LeMay S.   +13 more
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Visual memory correlates with AD biomarkers in cognitively unimpaired individuals. [PDF]

Alzheimers Dement
James TA, Zhao L, Xu H, Wu J, Schweidel DA, Goldstein FC, Levey AI, Qiu D, Loring DW, Hanfelt JJ, Lah JJ.   +10 more
europepmc   +1 more source

Mobilization of Haemophilus influenzae chromosomal markers by an Escherichia coli F' factor

Journal of Bacteriology, 1987
R. A. Deich, B. Green
semanticscholar   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Compensation effects between the apparent activation energy and pre-exponential factor in simple models of electrocatalytic hydrogen evolution.

Faraday Discuss
Fingerhut J, Snitkoff-Sol RZ, Albers M, Vos RE, van der Heijden O, Koper MTM.   +5 more
europepmc   +1 more source