Results 131 to 140 of about 22,331 (301)

Cold Orthogonal Translation: A Psychrophilic Pyrrolysyl‐tRNA Synthetase Boosts Genetic Code Expansion in E. coli

Advanced Science, EarlyView.
ABSTRACT Orthogonal translation systems (OTSs) enable site‐specific incorporation of non‐canonical amino acids (ncAAs) and are central to genetic code expansion. Current engineering strategies typically rely on hyperstable aminoacyl tRNA synthetase (aaRS) scaffolds to tolerate destabilizing mutations required for substrate diversification.
Nikolaj G. Koch, Peter Goettig, Michael A. Nash, Juri Rappsilber, Nediljko Budisa   +4 more
wiley   +1 more source

Nanocellulose Alleviates Intrahepatic Cholestasis of Pregnancy via Gut Microbiota‐Mediated Bile Acid Homeostasis

Advanced Science, EarlyView.
Nanocellulose, derived from microcrystalline cellulose (MCC) through sulfuric acid hydrolysis or mechanical grinding to produce CNC or CNF, was tested in a rat ICP model. Particularly, CNF improved gut microbiota composition, reduced secondary bile acid metabolism, and restored bile acid homeostasis through modulation of the gut–liver axis.
Muhua Yu, Hongjie Dai, Xiaocui Zhong, Qibin Li, Hui Yuan, Yang Yang, Daiyong Huang, Lei Zhang, Rui Ran, Tian He, Yuanzhi Huang, Silas Villas‐Boas, Sergey Tumanov, Richard D. Cannon, Boris Novakovic, Richard Saffery, Yuhao Zhang, Xiaojing Dong, Ting‐Li Han   +18 more
wiley   +1 more source

Ultrasound‐Activated Bifunctional Piezoelectric Hydrogel Dressings Promote Infected Wound Healing via Regulating Angiogenesis and Lymphangiogenesis

Advanced Science, EarlyView.
This study developed a double‐network hydrogel with piezoelectric properties, exhibiting excellent antibacterial activity and promoting fibroblast migration, angiogenesis, and lymphangiogenesis through piezoelectric stimulation, thereby accelerating the healing of infected chronic wounds.
Xiang Li, Zhen Ding, Zhihua Liu, Hao Chen, Jianyang Shan, Yanxuan Shao, Yaling Yu, Gen Wen   +7 more
wiley   +1 more source

A Deep Dive into f(R) Gravity Theory

, 2011
In this paper we have derived the behavior of deceleration parameter with respect to redshift in context of f(R) gravity in vacuum using Taylor expansion of derivative of action. Here we have obtained that the two first terms in Taylor expansion may describe the late time acceleration which is appeared by SNeIa without need of dark energy and dark ...
Asgari, Solmaz, Saffari, Reza
openaire   +2 more sources

Cosmological consequences of f(R) gravity

reservedIn this thesis, we are focusing on a theory called f(R) gravity, obtained from modifications of General Relativity (GR) by adding higher powers of the Ricci scalar into the standard GR action. By introducing additional terms to the action, we aim
ALI, AHMED ELSAYED ALI ELSAYED
core  

Godel universe in f(R,T) gravity

, 2019
In this study, we have considered Godel universe in the context of f(R,T) modified theory of gravity, where the gravitational Lagrangian is given by an arbitrary function of the Ricci scalar R and the trace of the energy-momentum tensor T.
Sofuoglu, DEĞER
core   +1 more source

Targeting METTL3 Attenuates Thyroid Inflammatory Injury by Restoring Th17/Treg Balance through a YTHDC2‐m6A‐Dependent KDR/VEGFA Loop

Advanced Science, EarlyView.
METTL3‐mediated m6A modification stabilizes KDR/Kdr mRNA through YTHDC2, amplifying the VEGFA‐KDR feedback loop and disturbing Th17/Treg balance. This pathway promotes persistent inflammation and tissue damage in patients with AIT, and inhibiting the METTL3‐KDR axis effectively disrupts this circuit, alleviating thyroid tissue injury and disease ...
Qingyi Hu, Huan Liu, Anwen Ren, Zimei Tang, Jie Tan, Wen Yang, Jie Ming, Tao Huang   +7 more
wiley   +1 more source

Anisotropic behavior of universe in $$f(R, L_m)$$ f ( R , L m ) gravity with varying deceleration parameter

European Physical Journal C: Particles and Fields
In this research study, we investigate the anisotropic behavior of the Universe using the framework of $$f(R, L_m)$$ f ( R , L m ) gravity. This modified gravity theory, represented by $$f(R, L_m)=\frac{R}{2}+L^\alpha _m+\beta $$ f ( R , L m ) = R 2 + L ...
Jeevan Pawde, Rahul Mapari, Vasudeo Patil, Dnyaneshwar Pawar   +3 more
doaj   +1 more source

f(R) gravity and Tsallis holographic dark energy

, 2020
The f(R) gravity theory is considered. It is a gravitational theory that generalizes the Einstein-Hilbert action. In this context, a holographic dark energy model is studied.
A. F. Santos, P. S. Ens
core   +1 more source

Friend, Not Foe: Lowered Tissue Reactivity to Long‐Term Polyimide Implants

Advanced Science, EarlyView.
The choice of optimal neural probe designs remains a major challenge in the field of neurotechnology. This study investigated the biocompatibility of several probe variations, including material, thickness, width, and implantation strategy. It highlights the clear advantage of soft polyimide probes over stiff silicon probes for better device ...
Corinne Orlemann, Laura M. De Santis, Paul Neering, Christian Boehler, Kirti Sharma, Arno Aarts, Tobias Holzhammer, Rik J. J. van Daal, Patrick Ruther, Maria Asplund, Roxana N. Kooijmans, Pieter R. Roelfsema   +11 more
wiley   +1 more source