Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Robust, conformal Cu<sub>2</sub>O coatings on polypropylene fabrics <i>via</i> atmospheric-pressure spatial atomic layer deposition. [PDF]
Gurbandurdyyev G +7 more
europepmc +1 more source
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Comparative Study of Mechanical Behavior and Failure Mechanisms in PA6- and PBT-Based Thermoplastic Fiber Metal Laminates. [PDF]
Katarzyna B, Dariusz B, Andrzej S.
europepmc +1 more source
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura +19 more
wiley +1 more source
Waterborne Polyurethane Reinforced with SiO<sub>2</sub>-Modified TiO<sub>2</sub>: Enhanced Mechanical Properties and Retained Hydrostatic Pressure Resistance. [PDF]
Wang S, Yao W, Lin X, Xu Y, Pei K, Lu Y.
europepmc +1 more source
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Bio-inspired functionalization of cotton fabric with ZnO NPs and senna didymobotrya leaf extracts for UV-protection and antibacterial activity. [PDF]
Moges G, Pawlos M, Weldegrum GS.
europepmc +1 more source
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley +1 more source
Comfort evaluation of dog apparel using 3D virtual fitting with clothing pressure across body size, movement and fabric. [PDF]
Kim J, Chae Y.
europepmc +1 more source

