Results 81 to 90 of about 203,404 (318)
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Intensive excavation and research over the course of decades have produced a very large dataset relating to Roman pottery from London. Research into the function of specific vessel forms has rarely been undertaken but information about the size, shape ...
Michael Marshall, Fiona Seeley
doaj +1 more source
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
This chapter considers the different woven manufacturing processes used in the production of apparel fabrics. It details the mainapparel fabric types and looks at the key performance requirements of those fabrics, in relation to both the weave structure
Redmore, Nicola, N.A. Redmore
core +1 more source
Chemical enhancement of footwear impressions in blood deposited on fabric - Evaluating the use of alginate casting materials followed by chemical enhancement [PDF]
Most footwear marks made in blood on a surface such as fabric tend to be enhanced in situ rather than physically recovered using a lifting technique prior to enhancement.
NicDaeid, N. +12 more
core +1 more source
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Development of hemp fabric reinforced composites [PDF]
One of the activities producing a destructive impact on the environment is uncontrolled or illegal timber harvesting. It is a response to high market demand due to the modernisation of lifestyles.
Misnon, Mohd Iqbal
core
Integration of textile fabric and coconut shell in particleboard
In this study, cotton fabric and coconut shell were integrated in particleboard to reduce the use of wood. Particleboards containing mixed rubberwood and coconut shell with an equal weight ratio have been integrated with various layers of cotton fabric ...
Islam, M. M. +7 more
core +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source

