Results 111 to 120 of about 86,750 (278)

High power post-compressed industrial-grade drivers for high harmonic generation [PDF]

open access: yesEPJ Web of Conferences
Recent advances in nonlinear post-compression using multi-pass cells and hollow-core capillaries combined with high-power Yb-doped amplifiers are reported, providing efficient access to high-average-power, few-cycle laser pulses for next-generation high ...
Natile Michele   +6 more
doaj   +1 more source

Podocyturia in Fabry disease

open access: yesJornal Brasileiro de Nefrologia, 2016
Fabry disease is a lysosomal storage disorder due to abnormalities in the GLA gene (Xq22). Such changes result in the reduction/absence of activity of the lysosome enzyme α-GAL, whose function is to metabolize globotriaosylceramide (Gb3). Renal disease is a major clinical outcome of the accumulation of Gb3.
Ester Miranda, Pereira   +4 more
openaire   +2 more sources

The frequency-dependent directivity of a planar Fabry-Perot polymer film ultrasound sensor [PDF]

open access: yes, 2007
A model of the frequency-dependent directivity of a planar, optically-addressed, Fabry-Perot (FP), polymer film ultrasound sensor is described and validated against experimental directivity measurements made over a frequency range of 1 to 15 MHz and ...
Beard, PC, Cox, BT
core  

Nanophotonic Biosensors and the Paradigm of Trans‐Scale Autonomous Bio‐Integrated Diagnostics for Addressing Health Complexities

open access: yesElectron, EarlyView.
Physics‐driven advances in optical nanobiosensors for rapid, miniaturized, and point‐of‐care diagnostics for next‐generation decentralized and personalized healthcare based on sensor intelligence. ABSTRACT Public health emergencies and the escalating burden of chronic diseases necessitate a paradigm shift from centralized laboratory testing to rapid ...
Vishal Chaudhary   +5 more
wiley   +1 more source

Nucleoside-Modified mRNA Encoding Alpha-Galactosidase A Ameliorates Fabry Disease Phenotypes in Human IPSC-Derived Cardiomyocytes. [PDF]

open access: yesAdv Sci (Weinh)
Human iPSC‐derived Fabry cardiomyocytes exhibited broad transcriptional dysregulation, apoptosis, mitochondrial dysfunction, impaired reactive oxygen species handling, altered contractility, and abnormal calcium transient decay, potentially mediated by phospholamban hyperphosphorylation.
Juchem M   +24 more
europepmc   +2 more sources

Inherited metabolic epilepsies–established diseases, new approaches

open access: yesEpilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Ultracold atoms in disordered potentials: elastic scattering time in the strong scattering regime

open access: yesNew Journal of Physics, 2019
We study the elastic scattering time ${\tau }_{{\rm{s}}}$ of ultracold atoms propagating in optical disordered potentials in the strong scattering regime, going beyond the recent work of Richard et al (2019 Phys. Rev. Lett. 122 100403).
Adrien Signoles   +10 more
doaj   +1 more source

Fluorene‐based blue emitters: On the path to electrically pumped organic lasers

open access: yesFlexMat, EarlyView.
Electrically pumped efficient operation remains unrealized, a major challenge in optoelectronics. Fluorene‐based blue‐emitting semiconductors are promising gain media, thanks to their structural tunability and favorable emission properties. This review summarizes recent advances, highlights their reliability and versatility in lasing, and outlines key ...
Yong Yan   +7 more
wiley   +1 more source

Myocardial Perfusion Defects in Hypertrophic Cardiomyopathy Mutation Carriers

open access: yesJournal of the American Heart Association, EarlyView., 2021
Background Impaired myocardial blood flow (MBF) in the absence of epicardial coronary disease is a feature of hypertrophic cardiomyopathy (HCM). Although most evident in hypertrophied or scarred segments, reduced MBF can occur in apparently normal segments.
Rebecca K. Hughes   +14 more
wiley   +1 more source

Recent progress and challenges in top‐emitting quantum dot light‐emitting diodes

open access: yesFlexMat, EarlyView.
This review summarizes recent advances in top‐emitting quantum‐dot light‐emitting diodes (TE‐QLEDs), including device architectures, microcavity engineering, angular‐emission management, and operational stability, highlighting optical–electrical–thermal co‐optimization as the key pathway toward reliable, high‐performance TE‐QLEDs. Abstract Top‐emitting
Chengyi Chen   +6 more
wiley   +1 more source

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