Targeting fibrosis in the treatment of lower urinary tract dysfunction
Abstract Benign prostatic hyperplasia (BPH) is a widely prevalent age‐associated disease that is the main contributor to lower urinary tract dysfunction (LUTD) in aging men. Although prostate fibrosis has been recognized as a contributor to BPH pathophysiology, there are not any clinically available therapeutics that target this aspect of disease ...
Ajinkya R Limkar +6 more
wiley +1 more source
A mulberry in female hypertrophic cardiomyopathy. [PDF]
Imataki O +3 more
europepmc +1 more source
Seasonal Forecasts of pH and Aragonite Saturation for the Bering Sea Shelf
Abstract The number of numerical model forecasts of ocean environmental conditions has greatly expanded in recent years, including biogeochemical variables. Forecasts can provide marine resource managers with advance warning of extreme events such as heatwaves and hypoxia, though forecast products are scarcer in high‐latitude environments.
D. J. Pilcher +5 more
wiley +1 more source
Treatment-related benefit and satisfaction in patients with Fabry disease in France: insight into patients' expectations and preferences from the prospective, non-interventional SATIS-Fab study. [PDF]
Lidove O +10 more
europepmc +1 more source
Abstract The present study reports on the variability of the post‐midnight ionosphere over the low‐latitude sector during the recovery phases of the May and October 2024 storms. Multi‐instrument observations, comprising global navigation satellite system total electron content (TEC), F‐layer peak height, electron density profiles, and column O/N2 ...
Rahul Rathi +5 more
wiley +1 more source
Grating based interferometric devices on a silicon photonic platform. [PDF]
Mikhail TJG, Swillam SM, Swillam MA.
europepmc +1 more source
Endothelial AGGF1 deficiency contributes to early vascular aging and age‐elevated blood pressure via inhibiting the SESN2/p‐eNOS pathway. Age‐dependent AGGF1 attenuation reduces its binding to the SESN2 promoter. SESN2 downregulation induces mitochondrial respiratory dysfunction and elevated mitochondrial ROS, thereby reducing eNOS phosphorylation ...
Weixin Lv +16 more
wiley +1 more source
Hydroxychloroquine-induced renal phospholipidosis manifesting as proximal tubulopathy in systemic lupus erythematosus. [PDF]
Manabe S +12 more
europepmc +1 more source
Effectiveness of Family Interventions in Bipolar Disorder: A Systematic Review
ABSTRACT Introduction Bipolar disorder (BD) is a chronic mental health condition characterized by extreme mood swings, which significantly affects both the individual and their family system. Given the psychosocial impact of BD on families, family interventions (FI) have emerged as a promising approach to improve treatment outcomes.
Madeha Umer +8 more
wiley +1 more source
A diagnostic challenge of advanced-stage cardiac Fabry disease without left ventricular hypertrophy: a case report. [PDF]
Suzuki M +7 more
europepmc +1 more source

