Results 151 to 160 of about 11,824,119 (390)
FEBS Letters, EarlyView.Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona +4 more
wiley +1 more source
GEPROS: Gestão da Produção, Operações e Sistemas, 2014 Márcio Roberto Costa +1 more
doaj +1 more source
THE DISSOCIATION OF VOLUNTARY AND EMOTIONAL MOVEMENTS OF THE FACE WITH SPECIAL REFERENCE TO EMOTIONAL PARESIS AS A PHYSICAL SIGN [PDF]
, 1931 I. M. Allen
openalex +1 more source
Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells
FEBS Letters, EarlyView.Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura +8 more
wiley +1 more source
RACE: Revista de Administração, Contabilidade e EconomiaA prática do estágio deve ser entendida como um complemento e não como algo rival à formação do estudante. Diante disso, o presente artigo tem por objetivo analisar os efeitos da realização de atividades de estágio curricular não obrigatório no ...
Sandro Eduardo Monsueto +2 more
doaj
Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1
FEBS Letters, EarlyView.Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri +5 more
wiley +1 more source
Protein kinase FAM20C—when subcellular localization matters
FEBS Letters, EarlyView.FAM20C is a Golgi‐resident kinase that phosphorylates proteins along the entire secretory pathway. The presence of potential FAM20C substrates in the cytoplasm or nucleus raises the question of how the kinase and its substrates encounter each other. Protein kinases achieve signaling specificity through consensus sequence recognition and subcellular ...
Francesca Noventa, Mauro Salvi
wiley +1 more source