Results 161 to 170 of about 8,918,962 (325)

Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?

Molecular Oncology, EarlyView.
Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley   +1 more source

Crítica, afetividade e criação de sentidos nos Estudos Organizacionais

Revista Espaço Acadêmico, 2013
O texto, que originalmente foi um exposição realizada no I Colóquio Internacional de Estudos Organizacionais, explora a atualidade do pensamento de Maurício Tragtenberg em suas proposições sobre a delinquência acadêmica.
Ana Paula Paes de Paula
doaj  

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

Molecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen, Chung‐Teng Wang, Jia‐Ming Chang, Ai‐Li Shiau, Gia‐Shing Shieh, Yau‐Lin Tseng, Yi‐Ting Yen, Tang‐Hsiu Huang, Li‐Hsin Cheng, Yu‐Chih Wu, Chao‐Liang Wu, Bing‐Hua Su, Pensee Wu   +12 more
wiley   +1 more source

Assessment of face mask use in peripartum women during the COVID-19 pandemic: an observational study. [PDF]

BMC Pregnancy Childbirth
Adusei S, Adams T, Stewart C.
europepmc   +1 more source

Adjourned Discussion on War Injuries of the Jaw and Face

, 1916
Percival P. Cole
openalex   +1 more source

Pole-Face Windings. Part I—Design [PDF]

, 1953
J.P. Blewett, Myrtle Hildred Blewett, W.H. Moore, L. W. Smith   +3 more
openalex   +1 more source

Face to Face [PDF]

Meta: Journal des traducteurs, 1982
openaire   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

Acceptability of self-completion versus face-to-face use of a vertebral fragility fracture clinical decision tool for use in older people with back pain in the UK. [PDF]

Arch Osteoporos
Khalid TY, Wilmott W, Shere C, Peters TJ, Drew S, Paskins Z, Clark EM.   +6 more
europepmc   +1 more source

Contributions of individual face features to face discrimination [PDF]

, 2017
Gordon, Gael E., Loffler, Gunter, Logan, Andrew J.   +2 more
core   +1 more source