Results 211 to 220 of about 8,918,962 (325)

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

Molecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski, Molly R. Danks, John P. Thomson, Morwenna Muir, Martin Lee, John C. Dawson, Ana T. Amaral, Juan Diaz‐Martin, David S. Moura, Javier Martin‐Broto, Ali Alsaadi, Donald M. Salter, Ailsa J. Oswald, Graeme Grimes, Larry Hayward, Ted R. Hupp, Karen Sisley, Paul H. Huang, Neil O. Carragher, Valerie G. Brunton   +19 more
wiley   +1 more source

Factors influencing bacterial viability on face masks and bactericidal effect of disinfection methods. [PDF]

Sci Rep
Shimamura Y, Ozaki M, Shinya M, Oishi R, Komuro M, Sasaki K, Tanaka H, Masuda S.   +7 more
europepmc   +1 more source

Case of Phlegmonous Erysipelas of the Face and Head, Occurring upon the Healing of Chronic Indolent Ulcers upon the Legs [PDF]

John Howard
openalex   +1 more source

THE CURE OF MULTIPLE WARTS ON THE FACE [PDF]

, 1919
C. Ind
openalex   +1 more source

The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features

Molecular Oncology, EarlyView.
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau, Stephan Forchhammer, Birgit Fehrenbacher, Lejla Mahmutovic, Marcus Scharpf, Gunnar Blumenstock, Martin Schaller, Irina Bonzheim, Shayan Khozooei, Mahmoud Toulany   +9 more
wiley   +1 more source

eHealth versus face-to-face support for remission of type 2 diabetes by calorie restriction (eHealth DIabetes remission Trial): study protocol for a non-inferiority parallel group randomised controlled trial. [PDF]

BMJ Open
Otten J, Tellström A, Schien C, Chninou Y, Lindholm L, Winkvist A, Liv P, Stomby A.   +7 more
europepmc   +1 more source

Plastic surgery of the face [PDF]

, 1921
Joseph C. Beck, Jacob Jesser
openalex   +1 more source

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

Molecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp, Wouter P. R. Verdurmen, Jonas V. Schaefer, Kari Kopra, Gabriela Nagy‐Davidescu, Elodie Richard, Marie‐Julie Nokin, Patrick Ernst, Rastislav Tamaskovic, Martin Schwill, Ralph Degen, Claudia Scholl, David Santamaria, Andreas Plückthun   +13 more
wiley   +1 more source

Exploring Associations Between Infant Attachment, Maternal Sensitivity, and Attention to Maternal Emotion Expressions. [PDF]

Dev Sci
Peltola MJ, Biro S, Huffmeijer R, Sinisalo H, Bakermans-Kranenburg MJ, van IJzendoorn MH.   +5 more
europepmc   +1 more source

The surgical treatment of post-radiation recurrent basal-cell carcinoma of the face and scalp

, 1951
Randell Champion, Robert Gibb
openalex   +1 more source