Results 51 to 60 of about 8,918,962 (325)

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Reporting of key audit matters: an analysis based on income smoothing in the brazilian electric power sector

Revista Ambiente Contábil
Purpose: This research aims to verify the impact of Key Audit Matters (KAMs) on income smoothing practices in Brazilian companies in the electric power sector. The final sample covers 33 companies in this sector, with the study period from 2016 to 2019,
Ana Claudia Santo Lima, Cleidinara Ribeiro Dias, Lúcio de Souza Machado, Carlos Henrique Silva do Carmo   +3 more
doaj   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

FEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Pediatric maxillofacial and oral traumatological emergencies in the department of stomatology, maxillofacial and plastic surgery of the university hospital of cocody (republic of IVORY COAST)

Heliyon, 2023
Introduction: Maxillofacial and oral trauma in children are a frequent reason for consultation in stomatology and maxillofacial surgery. Patients and methods: Retrospective study with a descriptive aim, carried out on the basis of an analysis of the ...
Konan Marc Koffi, Opokou Alexandre De Misères Ory, Sylvie Atsé-N'Guessan, Koffi Laurent Boka, Ake Lucien Jonathan Yapo, Affoué Linda Koffi, Lucien Asseke, Rokiatou Koné, Bakary Ouattara   +8 more
doaj  

Keynote: Italian Musicologists and the Challenge of Music Pedagogy

Musica Docta, 2016
The article offers an overview of the research and initiatives that have been carried out over the past 15 years by a group of Italian scholars in the field of Music Pedagogy.
Giuseppina La Face
doaj   +1 more source

Temporal networks of face-to-face human interactions

, 2013
The ever increasing adoption of mobile technologies and ubiquitous services allows to sense human behavior at unprecedented levels of details and scale. Wearable sensors are opening up a new window on human mobility and proximity at the finest resolution
A Barrat, A Barrat, A Gautreau, A Montis De, A Panisson, A Scherrer, A Vespignani, A Vàzquez, A Wasserman, A.-L. Barabàsi, A.-L. Barabási, C Cattuto, C Song, D Balcan, D Brockmann, D Lazer, D Rybski, D Watts, G Caldarelli, G Chowell, G Kossinets, G Krings, J Giles, J Moody, J Stehlé, J Stehlé, J.-P. Eckmann, J.-P. Onnela, JF Padgett, JM Read, K Zhao, L Isella, L Isella, M McPherson, M Seifi, M. Salathé, M.E.J. Newman, MC González, MJ Lubbers, P Bajardi, P Holme, R Anderson, R Groenevelt, R Pastor-Satorras, R Pastor-Satorras, RD Malmgren, S Blower, SA Hill, SN Dorogovtsev, Special issue of Science on Complex networks and systems, V Nicosia, X Zhang   +51 more
core   +2 more sources

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Extensive primary oral malignant melanoma: A case report with review of literature

Advances in Oral and Maxillofacial Surgery, 2022
Oral mucosal melanoma is an exceptionally rare tumor with the tendency to metastasize and locally invade tissues more readily than other malignant tumor of the oral cavity.
Walid Bijou, Mohammed Laachoubi, Youssef Oukessou, Sami Rouadi, Reda Abada, Mohamed Roubal, Mohamed Mahtar   +6 more
doaj  

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

FEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke, Izadora Volpato Rossi, Marcel I. Ramirez   +2 more
wiley   +1 more source

Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation

FEBS Letters, EarlyView.
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley   +1 more source