Results 61 to 70 of about 12,024,061 (386)

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

open access: yesFEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz   +5 more
wiley   +1 more source

A relação entre as políticas de gênero e a criação de empresas por mulheres

open access: yesRegepe Entrepreneurship and Small Business Journal, 2023
Objetivo: analisar os efeitos das políticas de gênero na criação de empresas por mulheres. Metodologia/abordagem: abordagem quantitativa, com dados secundários extraídos da Pesquisa de Informações Básicas Municipais (MUNIC); e dados públicos de CNPJ, da
Daiane Martins Teixeira   +2 more
doaj   +1 more source

Face to Face in Costa Rica [PDF]

open access: yes, 2010
While still in the midst of their study abroad experiences, students at Linfield College write reflective essays. Their essays address issues of cultural similarity and difference, compare lifestyles, mores, norms, and habits between their host countries
Weller, Felicia
core   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

open access: yesFEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer   +7 more
wiley   +1 more source

Face to face

open access: yesMiędzy Oryginałem a Przekładem, 2022
FACE TO FACE: FRANCO BELTRAMETTI AND JUDITH DANCIGER: A COUPLE OF TRANSLATORS In 1973 Franco Beltrametti, a Swiss author strictly connected to both the authors of the Beat Generation and to those of the Italian neo-avant-garde (Gruppo 63), published a bilingual collection of poems in Italian and English that he significantly titled Face to face ...
openaire   +3 more sources

Time perception: A study of young Brazilian workers [PDF]

open access: yesTourism & Management Studies, 2016
Given the importance of time as a category of analysis in organisational research, this study’s objective was to analyse the time perceptions of young Brazilian workers. The study was guided by the five time dimensions proposed by Bluedorn and Jaussi (
Kely César Martins de Paiva   +1 more
doaj   +1 more source

The relationship between gender policies and the creation of businesses by women

open access: yesRegepe Entrepreneurship and Small Business Journal, 2023
Objective: to analyze the effects of gender policies on women's business creation. Methodology/approach: quantitative approach, with secondary data extracted from the Municipal Basic Information Survey (MUNIC); and public CNPJ data from the Federal ...
Daiane Martins Teixeira   +2 more
doaj   +1 more source

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

open access: yesFEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur   +5 more
wiley   +1 more source

Laser Endoscopic Microsurgery of Laryngeal Cancers

open access: yesInternational Archives of Otorhinolaryngology, 2014
Introduction The aim of our study is to present our experience in treating laryngeal cancers with endoscopic CO2 laser surgery. Materials and Methods This retrospective study was conducted from January 2008 to December 2012 at Antoine ...
Sereme Moustapha   +3 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

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