Results 61 to 70 of about 3,325,804 (208)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Selectivity of face distortion aftereffects for differences in expression or gender

open access: yesFrontiers in Psychology, 2012
The perceived configuration of a face can be strongly biased by prior adaptation to a face with a distorted configuration. These aftereffects have been found to be weaker when the adapt and test faces differ along a number of dimensions. We asked whether
Megan eTillman, Michael eWebster
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Supporting Integrated and Comprehensive Approaches to Climate Change Adaptation in Africa [PDF]

open access: yes, 2010
The Africa Adaptation Programme (AAP) has been designed to support the long-term efforts of targeted countries to further develop their capability to successfully identify, design and implement holistic adaptation and disaster risk reduction programmes ...
The Africa Adaptation Programme (AAP)
core  

Reduced face aftereffects in autism are not due to poor attention.

open access: yesPLoS ONE, 2013
This study aimed to determine why face identity aftereffects are diminished in children with autism, relative to typical children. To address the possibility that reduced face aftereffects might reflect reduced attention to adapting stimuli, we ...
Louise Ewing   +4 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

The multiple-faces effect: preliminary studies / O fenômeno de muitas-faces: investigações preliminares

open access: yesPsicologia: Reflexão e Crítica, 2005
The multiple-faces effect was first investigated at the blind spot using familiar faces. We analyzed the effect into 4 categories: 1) disappearance/darkening/whitening of face parts; 2) variation in size of face parts; 3) perception of movement /change ...
Maria Lúcia de Bustamante Simas   +1 more
doaj  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Valuing adaptation under rapid change [PDF]

open access: yes, 2013
The methods used to plan adaptation to climate change have been heavily influenced by scientific narratives of gradual change and economic narratives of marginal adjustments to that change.
Celeste Young   +2 more
core  

Do infants represent the face in a viewpoint-invariant manner? Neural adaptation study as measured by near-infrared spectroscopy

open access: yesFrontiers in Human Neuroscience, 2011
Recent adult fMRI studies reported that face sensitive cortical areas showed attenuated responses to the repeated presentation of an identical facial image compared to the presentation of different facial images (fMRI-adaptation effects: e.g., Andrews ...
Megumi eKobayashi   +7 more
doaj   +1 more source

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