Frailty Exacerbates Disability in Progressive Multiple Sclerosis
ABSTRACT Background To evaluate frailty in severe progressive multiple sclerosis (PMS) and to investigate the underlying mechanisms. Methods This prospective, cross‐sectional, multicenter study enrolled a late severe PMS group requiring skilled nursing (n = 53) and an age, sex, and disease duration‐matched control PMS group (n = 53).
Taylor R. Wicks +10 more
wiley +1 more source
Assessing the performance of a new generic measure of health related quality of life for children and refining it for use in health state valuation [PDF]
Purpose: The aims of this research were to pilot and assess the performance of a new generic paediatric health related quality of life measure and to refine the measure to be amenable to health state valuation to make it suitable for use in economic ...
Stevens, K.
core
Face and Content Validity of the Pictorial Scale of Perceived Water Competence in Young Children. [PDF]
Morgado LS +7 more
europepmc +1 more source
Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin +2 more
wiley +1 more source
Validitas, Reliabilatas Dan Dampak Pembelajaran Terhadap Tes Objective Structured Clinical Examintaion (OSCE) [PDF]
Objective Structured Clinical Examination (OSCE) was developed for the first time by Harden at1975 which was used for evaluating clinical skill ability of OSCE Implementation that could give learning positive and negative impact.
Ashaeryanto, A. (Ashaeryanto)
core
ABSTRACT Objective Plasma fibrinogen is essential in thrombosis and fibrinolysis, yet its dynamic changes pre‐ and post‐intravenous thrombolysis (IVT) for predicting brain injury severity and prognosis in acute ischemic stroke (AIS) patients remain unclear.
Wenhai Zhai +28 more
wiley +1 more source
Psychometric analysis of the ambulatory care learning education environment measure (ACLEEM) in Iran [PDF]
Background: Examining educational environment (academic and clinical) by means of a valid, reliable and comprehensive questionnaire is a major key in achieving a highly qualified student - oriented curricula.
Azaminejad, Faranak +8 more
core +3 more sources
Background: Psychosocial aspects of balance including self-perception, behaviors, and experiences, have been found to contribute to activity limitations and participation restrictions in adults.
Beckett, Jillian L., Harmon, Ashlee A.
core +1 more source
Assessment of a high-fidelity, virtual reality-based, manual small-incision cataract surgery simulator: A face and content validity study. [PDF]
Nair AG +4 more
europepmc +1 more source
The McCance Brain Care Score and Mortality: Evidence From a Large‐Scale Population‐Based Cohort
ABSTRACT Objectives This study aimed to examine the relationship between the McCance Brain Care Score (BCS) and mortality in the general population. Methods We conducted a prospective, population‐based cohort study using data from the UK Biobank. Participants with complete data enabling calculation of BCS and full mortality information were included ...
Zhiqiang Xu, Xiaoxiao Wang, Nan Li
wiley +1 more source

