FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Face Detection Algorithm Based on Double-Channel CNN with Occlusion Perceptron. [PDF]
Comput Intell Neurosci, 2022 Li Y.
europepmc +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Intelligent lecture recording system based on coordination of face-detection and pedestrian dead reckoning. [PDF]
PeerJ Comput Sci, 2022 Wang H, Hu J.
europepmc +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Making Machine Learning Accessible for Developmental Science: The Case of Automated Face Detection. [PDF]
Dev SciNikolov TY +5 more
europepmc +1 more source
Hybrid Pyramid Convolutional Network for Multiscale Face Detection. [PDF]
Comput Intell Neurosci, 2021 Hou S, Fang D, Pan Y, Li Y, Yin G.
europepmc +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
STFANet: A spatial and temporal feature aggregation network for fake face detection in videos. [PDF]
PLoS OneYao G, Yang G, Liu X, Chen L.
europepmc +1 more source
Intact face detection in young patients with major depressive disorder revealed by the face-specific N170 component. [PDF]
Sci Rep, 2022 Chen Y, Tong F, Zhao L, Sun G.
europepmc +1 more source