Results 271 to 280 of about 1,389,395 (324)

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Microplastic Detection in Lawaye River, San Juan, Batangas City, Philippines Using Front-Face Fluorescence Spectroscopy

open access: gold
Jowi Tsidkenu P. Cruz   +5 more
openalex   +1 more source

Detecting Faces With Face Masks

2021 44th International Conference on Telecommunications and Signal Processing (TSP), 2021
This paper deals with the evaluation of several methods for face detection when the face is covered by a mask. The methods evaluated are Haar cascade and Histogram of Oriented Gradients as feature-based approaches, Multitask Cascade Convolutional Neural Network, Max Margin Object Detection and TinyFace as convolutional neural network based approaches ...
Jiri Prinosil, Ondrej Maly
openaire   +1 more source

Face Detection: A Survey

Computer Vision and Image Understanding, 2001
Summary: We present a comprehensive and critical survey of face detection algorithms. Face detection is a necessary first-step in face recognition systems, with the purpose of localizing and extracting the face region from the background. It also has several applications in areas such as content-based image retrieval, video coding, video conferencing ...
Hjelmås, Erik, Low, Boon Kee
openaire   +2 more sources

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