Results 81 to 90 of about 5,519,699 (249)

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Spoofing attempt detection using gaze colocation [PDF]

open access: yes, 2013
Spoofing attacks on biometric systems are one of the major impediments to their use for secure unattended applications. This paper presents a novel method for face liveness detection by tracking the gaze of the user with an ordinary webcam.
Ali, Asad, Deravi, Farzin, Hoque, Sanaul
core  

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

2D Versus 3D Colour Space Face Detection [PDF]

open access: yes, 2003
Computer vision is one out of many areas that want to understand the process of human functionality and copy that process with intention to complement human life with intelligent machines.
Solina, Franc, Kovač, Jure, Peer, Peter
core   +1 more source

An Experimental Study of Facial Recognition Performance for Real-Time UAV Surveillance in Urban Environments

open access: yesPakistan Journal of Engineering Technology & Science
In today’s era, facial recognition is common in every aspect of life whether in smartphones, security, attendance management, healthcare, and law enforcement.
Muhammad Shafiq   +3 more
doaj   +1 more source

A Modular System for Detection, Tracking and Analysis of Human Faces in Thermal Infrared Recordings

open access: yesSensors, 2019
We present a system that utilizes a range of image processing algorithms to allow fully automated thermal face analysis under both laboratory and real-world conditions.
Marcin Kopaczka   +3 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Intelligent Lecturer Tracking and Capturing System Based on Face Detection and Wireless Sensing Technology

open access: yesSensors, 2019
In this paper, we propose an intelligent lecturer tracking and capturing (ILTC) system to automatically record course videos. Real-time and stable lecturer localization is realized by combining face detection with infrared (IR) thermal sensors ...
Tan-Hsu Tan, Tien-Ying Kuo, Huibin Liu
doaj   +1 more source

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