Results 81 to 90 of about 132,571 (310)

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Effect of Mouth Mask and Face Shield on Speech Spectrum in Slovak Language

open access: yesApplied Sciences, 2021
In this paper, with the aim of assessing the deterioration of speech intelligibility caused by a speaker wearing a mask, different face masks (surgical masks, FFP2 mask, homemade textile-based protection and two kinds of plastic shields) are compared in ...
Vojtech Chmelík   +3 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

COVID-19, Face Mask Usage and Cooperation

open access: yes, 2020
This study will investigate the relationship between face mask usage and cooperative behavior in the US population during the Covid-19 pandemic. Social preferences are assumed to be one of the main determining factors of face mask usage.
Chan Qi-Yu   +4 more
core   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Ventilation with a full face mask in rhinoplasty: A new method

open access: yesMedicine Science
Effectual mask ventilation is necessary for confident airway administration in the course of general anesthesia. Following septoplasty procedures, nasal packing is often utilized and after rhinoplasty operations, plaster is often used on the nose. A face
Erdinc Koca, Cigdem Firat Koca
doaj   +1 more source

An epidemiological study on face masks and acne in a Nigerian population.

open access: yesPLoS ONE, 2022
BackgroundAcne vulgaris is a skin disorder that affects males and females with significant impact on quality of life. The onset of the COVID-19 pandemic led to a series of non-pharmaceutical interventions globally to reduce the spread of the virus ...
Olanrewaju Falodun   +5 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Personalized real face 3D mask

open access: yes, 2023
The aim of this research was to come up with a three-dimensional personalized face mask that is literally for use in medical facilities by patients. This was therefore achieved through scanning the face of the person whose mask is being prepared, and the
Jiang, Xingyue
core  

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy