Results 61 to 70 of about 3,123,613 (291)

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Infant Eye Gaze While Viewing Dynamic Faces

open access: yesBrain Sciences, 2021
Research using eye tracking methods has revealed that when viewing faces, between 6 to 10 months of age, infants begin to shift visual attention from the eye region to the mouth region.
Lisa M. Oakes   +4 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Model-Based Real-Time Head Tracking

open access: yesEURASIP Journal on Advances in Signal Processing, 2002
This paper treats real-time tracking of a human head using an analysis by synthesis approach. The work is based on the Structure from Motion (SfM) algorithm from Azarbayejani and Pentland (1995).
Ström Jacob
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Telemedicine System for Monitoring Heart Rate Using Independent Component Analysis in Videos

open access: yesLatin-American Journal of Computing, 2017
Heart is the organ responsible for providing blood, oxygen and nutrients through the human body, their initial monitoring was reflected in heart rate value, this measurement is a possible irregularity within the organism.
Karla Portilla   +3 more
doaj  

Optimizing the Interaction System for Treadmill Video Games Using a Smartphone’s Front Camera

open access: yesSensors
This paper introduces a lightweight and accessible interaction system for treadmill-based video games, relying solely on facial tracking via a smartphone’s front camera.
Micaela Yanet Martin   +3 more
doaj   +1 more source

Tracking of stationary face phantom.

open access: yes, 2019
Tracking curves represented by center of mass of the 3D point cloud (PC) obtained from a TCL2 tracking of a stationary face phantom during an mMR Biograph MRI scan.
Andreas H. Ellegaard (6616334)   +10 more
core   +1 more source

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