Results 151 to 160 of about 431,332 (277)

Ultrasound‐Activated Piezoelectric Neuroimmune Hydrogel Orchestrates Neurogenesis‐Macrophage Crosstalk in Diabetic Wound Healing

Advanced Science, EarlyView.
In this work, we design an ultrasound‐activated piezoelectric hydrogel platform (AOEF@AP5+US) that reprograms neurogenesis‐macrophage crosstalk as an integrated strategy to overcome the intertwined barriers of chronic inflammation, peripheral neuropathy, and impaired regeneration in diabetic wounds.
Kai Wang, Shaowen Zhuo, Binyu Song, Jinan Chen, Xin Zhao, Sijia Li, Shuang You, Dong Jiang, Yuedong Chen, Juanli Dang, Tong Wang, Baolin Guo, Zhou Yu, Baoqiang Song   +13 more
wiley   +1 more source

Internal Acoustic Meatus: Morphological Peculiarities and Clinical Implications. [PDF]

Audiol Res
Babuci A, Ashkar L, Zorina Z, Capcelea S, Stratulat S, Catereniuc I, Gitu L, Botnaru D, Buracovschi M, Cemortan I, Chele N, Mostovei A, Motelica G, Dabija I, Strisca S, Dandara M, Nastas L, Beliniuc S, Stepco E, Lozovanu S, Cheptanaru O, Lehtman S.   +21 more
europepmc   +1 more source

Redirecting Monocyte Differentiation With Engineered Extracellular Vesicles for Glioma Immunotherapy

Advanced Science, EarlyView.
A dual‐targeting engineered extracellular vesicles (M1‐CS‐EVs) platform is developed to redirect monocytes differentiation into anti‐tumor macrophages for glioma immunotherapy. This nanoplatform combines CAR‐mediated tumor recognition with localized CD47 blockade, leading to synergistic immune activation and potent suppression of tumor progression in ...
Yuanwei Pan, Xuan Liu, Qian‐Fang Meng, Lei Cao, Rongrong Li, Yangtao Xu, Jing Zhang, Chenchen Zhao, Lang Rao, Chen Yu   +9 more
wiley   +1 more source

Acute otitis media complicated by peripheral facial nerve palsy in an adult: A case report. [PDF]

IDCases
Afzal A, Owais M, Manzoor MU, Asif A, Shuaib R, Ahmad MU.   +5 more
europepmc   +1 more source

Latent Diffusion Process With Mechanistic Guidance For Designing Functionally Graded Metamaterials With Perfect Connectivity

Advanced Science, EarlyView.
A latent diffusion‐based framework is proposed for designing functionally graded metamaterials with perfect connectivity. By integrating vector‐quantized latent representations with mechanistic guidance, the framework enables accurate inverse design toward target elastic properties.
Jongbin Yu, Dosung Lee, Namjung Kim
wiley   +1 more source

Cerebellar abscess complicating chronic suppurative otitis media: An unusual route of intracranial spread. [PDF]

Radiol Case Rep
Soldo L, Grgić S, Pehar I, Kokić M, Dervišević Bevanda S, Redžić L, Sarić Zolj B, Grubeša Raguž S, Dalmatin Dragišić M.   +8 more
europepmc   +1 more source

Rhoifolin Alleviates Ulcerative Colitis by Targeting NMNAT1 and Activating SIRT1‐FOXO1 Signaling to Enhance ILC3s Effector Function

Advanced Science, EarlyView.
Rhoifolin directly targets NMNAT1, thereby activating nicotinamide salvage pathway and promoting intracellular NAD+ biosynthesis. Elevated NAD+ levels enhance SIRT1 activity, leading to FOXO1 deacetylation and nuclear translocation. Nuclear FOXO1 subsequently binds to the IL‐22 promoter, upregulating IL‐22 transcription and potentiating ILC3 effector ...
Hongqiong Yang, Yishu Zhang, Sijia Feng, Xiaoqing Ma, Jiayi Feng, Junwei Wang, Jialin Gao, An Pan, Dapeng Wu, Kang Ding, Caijuan Zheng, Qi Lv, Lihong Hu   +12 more
wiley   +1 more source

Quantifying the Severity of Facial Trauma in a Bulgarian Cohort Using the Comprehensive Facial Injury Score. [PDF]

Reports (MDPI)
Ralev V.
europepmc   +1 more source

Chimeric IL‐6/4R‐LL37 Engineered Macrophages Achieve Synchronized Inflammation Control and Antimicrobial Defence in Sepsis

Advanced Science, EarlyView.
Engineered macrophages programmed in situ by LNP‐delivered IL‐6/4 fusion and LL37 mRNAs simultaneously dampen cytokine storm, promote M2‐like repair, and enhance direct bacterial killing in sepsis. This combinatorial strategy restores T cell and macrophage function, lowers organ bacterial burden, and improves survival, highlighting a precision, host ...
Tianyang Jie, Zheyu Zhang, Hao Zhang, Linke Bian, Penglong Zheng, Sijia Zhou, Minqi Wang, Mingyu Qu, Yufei Wang, Xinhua Qu, Bing Yue   +10 more
wiley   +1 more source

Development of the Surgical Implantation and Fixation of an Implanted Middle Ear Microphone, the "UmboMic," in Cadaveric Sheep. [PDF]

J Assoc Res Otolaryngol
Comens IC, Zhou C, Nguyen DL, Wawrzynek EF, Zhang JZ, Kymissis I, Welling DB, Lang JH, Nakajima HH, Olson ES.   +9 more
europepmc   +1 more source