Results 221 to 230 of about 39,775 (309)

Brown Adipocyte Sheets Alleviate Myocardial Ischemia–Reperfusion Injury Through NRG4–ErbB4–Dependent Ferroptosis Inhibition

open access: yesAdvanced Science, EarlyView.
Brown adipocyte sheets are engineered to protect the heart against myocardial ischemia–reperfusion injury by restraining ferroptosis. Upon transplantation onto the cardiac surface, they improve cardiac function, limit infarction and fibrosis, and enhance angiogenesis.
Lifu Sun   +6 more
wiley   +1 more source

Hierarchical Ordering Induced Ultrahigh Cryogenic Strength and Strain Hardening in a Ni2CoFeV Medium‐Entropy Alloy

open access: yesAdvanced Science, EarlyView.
A tri‐phase Ni2CoFeV medium‐entropy alloy with fcc, κ, and L12 phases achieves exceptional cryogenic strength‐ductility synergy at 77 K. It delivers a yield strength of 1.4 GPa, an ultimate tensile strength of 2.07 GPa and a tensile ductility of 28%.
Lei Gu   +4 more
wiley   +1 more source

Hierarchical Twin Networks Enable Exceptional Strength and Fracture Toughness in Titanium

open access: yesAdvanced Science, EarlyView.
A commercial‐purity titanium with hierarchical ultrafine twin structures delivers an exceptional combination of fracture toughness (KJIc) of 187 MPa·m1/2 and specific yield strength of 140 MPa·cm3·g−1, in which pre‐engineered high‐density twin boundaries stimulate massive and dislocations to blunt crack tip.
Xiao‐Wei Zou  
+3 more
wiley   +1 more source

Nucleic Acid Therapeutics for “Undruggable” Cancer Targets: Mechanisms, Challenges, and Prospects

open access: yesAdvanced Science, EarlyView.
Nucleic acid therapeutics bypass the structural limitations of conventional drugs by targeting mRNA rather than proteins. This review examines how antisense oligonucleotides, siRNAs, miRNAs, aptamers, and mRNA vaccines intervene against historically undruggable oncoproteins including Ras, MYC, and p53, highlighting mechanistic advances, delivery ...
Feng Xu   +6 more
wiley   +1 more source

Association Between Trauma Mechanism and Mandibular Fracture Pattern: A 13-Year Retrospective Analysis at a Regional Trauma Center. [PDF]

open access: yesCraniomaxillofac Trauma Reconstr
Giannunzio GA   +4 more
europepmc   +1 more source

Oxygen Vacancy‐Enriched Platinum Single‐Atom Nanozyme Wrapped in Nanoislands: Unlocking Catalytic Activity and Reprogramming Redox Microenvironment for Osteonecrosis Repair

open access: yesAdvanced Science, EarlyView.
CeO2‐x/Pt single‐atom nano‐island is constructed via low‐temperature reduction, featuring abundant oxygen vacancies and an island–sea structure. It delivers outstanding multi‐enzyme‐mimetic activity and ROS‐scavenging efficiency. Density functional theory reveals optimized electronic structures and reaction pathways.
Yang Zhu   +12 more
wiley   +1 more source

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