Results 41 to 50 of about 309,472 (263)
Asymmetric game perfect graphs and the circular coloring game of weighted graphs [PDF]
, 2011 Zacharopoulos P. Asymmetric game perfect graphs and the circular coloring game of weighted graphs.
Zacharopoulos, Panagiotis
core
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Perception and Deception: Human Beauty and the Brain
Behavioral Sciences, 2019 Human physical characteristics and their perception by the brain are under pressure by natural selection to optimize reproductive success. Men and women have different strategies to appear attractive and have different interests in identifying beauty in ...
Daniel B. Yarosh
doaj +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Configural and featural information in facial-composite images [PDF]
, 2014 Eyewitnesses are often invited to construct a facial composite, an image created of the person they saw commit a crime that is used by law enforcement to locate criminal suspects.
Kearley, Kevin +39 more
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Weaver Syndrome: A Rare Cause of Neonatal Macrosomia and Dysmorphism. A Case Report. [PDF]
Batna Journal of Medical SciencesWeaver syndrome is a rare genetic disorder characterized by abnormally excessive growth both in utero and postnatally. It is associated with a mutation in the EZH2 gene, which leads to accelerated bone development and other clinical manifestations such
Fadila BENDAOUD, Hemza GUELLOUH
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FEBS Open Bio, EarlyView.Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
Odd facial total-coloring of unicyclic plane graphs [PDF]
Discrete Mathematics Letters, 2022 Július Czap
doaj +1 more source