Results 81 to 90 of about 237,985 (287)

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Expression Conditional GAN for Facial Expression-to-Expression Translation

open access: yes, 2019
In this paper, we focus on the facial expression translation task and propose a novel Expression Conditional GAN (ECGAN) which can learn the mapping from one image domain to another one based on an additional expression attribute. The proposed ECGAN is a
Chen, Xinya   +6 more
core   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Facial length and angle feature recognition for digital libraries.

open access: yesPLoS ONE
With the continuous progress of technology, facial recognition technology is widely used in various scenarios as a mature biometric technology. However, the accuracy of facial feature recognition has become a major challenge.
Shuangyan Li   +3 more
doaj   +1 more source

Effects of emotional expressions in recognizing unfamiliar faces

open access: yesJournal of Human Environmental Studies, 2010
The role of the facial expression of emotions on face recognition was investigated by analyzing the effects of happy and angry expressions on identity and facial expression recognition memory task.
Mika Itoh   +2 more
doaj   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Facial Expression Recognition Based on Multi-dataset Neural Network [PDF]

open access: yesRadioengineering, 2020
Facial activity is the most powerful and natural means for understanding emotional expression for humans. Recent years, extensive efforts have been devoted to facial expression recognition by using neural networks.
B. Yang, Z. LI, E. Cao
doaj  

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