Results 41 to 50 of about 231 (215)

Fibroblast morphology, growth rate and gene expression in facial melasma

open access: yesAnais Brasileiros de Dermatologia, 2022
Background: In addition to melanocytic hyperfunction, changes are observed in the upper dermis of melasma, and fibroblasts play a central role in collagen synthesis and pigmentation induction.
Ana Cláudia Cavalcante Espósito   +3 more
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Development of an Interactive Digital Human with Context-Sensitive Facial Expressions

open access: yesSensors
With the increasing complexity of human–computer interaction scenarios, conventional digital human facial expression systems show notable limitations in handling multi-emotion co-occurrence, dynamic expression, and semantic responsiveness.
Fan Yang   +4 more
doaj   +1 more source

Muecas: A Multi-Sensor Robotic Head for Affective Human Robot Interaction and Imitation

open access: yesSensors, 2014
This paper presents a multi-sensor humanoid robotic head for human robot interaction. The design of the robotic head, Muecas, is based on ongoing research on the mechanisms of perception and imitation of human expressions and emotions.
Felipe Cid   +3 more
doaj   +1 more source

Analytical Method of Assessing Psycho-Emotional State

open access: yesЭкспериментальная психология, 2020
The article presents the results of series of myographic studies. On the basis of diagnostics of mimic reactions and use of matrix method the analytical method of research of the psycho-emotional state was developed.
V.V. Volov, H.V. Zalevsky
doaj   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Facial Expression Synthesis Through Facial Expressions Statistical Analysis

open access: yes, 2006
Publication in the conference proceedings of EUSIPCO, Florence, Italy ...
openaire   +1 more source

Geometry Guided Adversarial Facial Expression Synthesis [PDF]

open access: yesProceedings of the 26th ACM international conference on Multimedia, 2018
Facial expression synthesis has drawn much attention in the field of computer graphics and pattern recognition. It has been widely used in face animation and recognition. However, it is still challenging due to the high-level semantic presence of large and non-linear face geometry variations. This paper proposes a Geometry-Guided Generative Adversarial
Song, Lingxiao   +4 more
openaire   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

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