Results 31 to 40 of about 40,375 (257)

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

The US‐Mexico Border Wall Height Extension Is Associated With Increased Incidence and Severity of Facial Trauma

Laryngoscope Investigative Otolaryngology
Objective The recent United States (US)‐Mexico border wall height extension has been associated with greater migrant neurological and musculoskeletal morbidity after falls. However, the impact on facial trauma has yet to be characterized. Methods In this
Alexander Tenorio, Gautam R. Produturi, Farhoud Faraji, Víctor deCos, Carson P. McCann, Amanda A. Gosman, David B. Hom, Jay J. Doucet, Todd W. Costantini, Alexander A. Khalessi, Joseph D. Ciacci   +10 more
doaj   +1 more source

CHARACTERISTICS OF THE CIRCUMSTANCES OF FORMATION, CLINICAL AND MORPHOLOGICAL MANIFESTATIONS, COURSE AND ASSESSMENT OF THE DEGREE OF GRAVITY OF DAMAGE IN CASES OF FACIAL INJURIES IN CHILDREN AND ADOLESCENTS

Неонатологія, хірургія та перинатальна медицина
This study aims to examine the characteristics of facial injuries in children and adolescents by analyzing age- and gender-specific variations to enhance forensic medical assessments.
В. Мішалов, С. Козлов, О. Гуріна, М. Гараздюк , П. Плевінскіс, М. Зубко   +5 more
doaj   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

A 5-year comprehensive evaluation of maxillofacial injuries in polytrauma patients at a tertiary hospital – an epidemiological study

Acta Odontologica Scandinavica
Objectives: To report and analyze the pattern of maxillofacial injuries in trauma victims and to define the role of a maxillofacial surgeon in an emergency trauma care team. Materials and methods: Trauma patients reported and reporting to the casualty
Pradeep Muralidhar, Vinod Bandela, Abdul Ahad Ghaffar Khan, Shahi Jahan Shah, Abosofyan Salih Atta Elfadeel, Ram B Basany, Devi Singh Amgoth, Shilpa Param   +7 more
doaj   +1 more source

Location‐Specific Hematoma Volume Predicts Early Neurological Deterioration in Supratentorial ICH

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Early neurological deterioration (END) adversely affects outcomes in patients with intracerebral hemorrhage (ICH). This study aimed to determine the location‐specific hematoma volumes for END in supratentorial ICH patients. Methods We retrospectively analyzed supratentorial ICH patients presenting from two prospective cohorts.
Zuoqiao Li, Guilin Meng, Zijie Wang, Xiao Hu, Jing Cheng, Chu Chen, Tiannan Yang, Jiaxin Luo, Zizhen Meng, Xueyun Liu, Qi Li   +10 more
wiley   +1 more source

Associated injuries in patients with facial fractures: a review of 604 patients

The Pan African Medical Journal, 2013
Facial fractures may be associated with concomitant lesions of other parts of body with some of these injuries being life-threatening. This retrospective study reports the types of associated injury and the factors influencing their occurrence, in ...
Rasmanë Boë go, Patrick Dakoure, Leon Blaise Savadogo, Antoine Toua Coulibaly, Kampadilemba Ouoba   +4 more
doaj   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani, Emmanuel Barbeau, Béatrice Lemesle, Emilie Milongo‐Rigal, Sophie Fernandez, Sandrine Charpentier, Jean‐François Albucher, Nicolas Raposo, Fabrice Bonneville, Patrice Péran, Jérémie Pariente   +10 more
wiley   +1 more source