Results 81 to 90 of about 352,635 (287)

Introducing Borsantrazole: A Trifunctional Boron‐Based Pyrazole That Extends the Lifespan of Amyotrophic Lateral Sclerosis Mice

open access: yesAdvanced Science, EarlyView.
Herein we report a boron‐based pyrazole, (Borsantrazole ‐ a small molecule that selectively targets oxidative stress) that significantly increases survival, reduces weight loss, delays disease onset, and affects global protein changes in the SOD1‐G37R mouse model of ALS.
Nitesh Sanghai   +9 more
wiley   +1 more source

Feature fusion for facial landmark detection

open access: yesPattern Recognition, 2014
Abstract Facial landmark detection is a crucial first step in facial analysis for biometrics and numerous other applications. However, it has proved to be a very challenging task due to the numerous sources of variation in 2D and 3D facial data.
Panagiotis Perakis   +2 more
openaire   +2 more sources

RPLP2 Mediates the Beneficial Effects of Exercise on Stress Resistance Through Muscle–Brain Communication

open access: yesAdvanced Science, EarlyView.
A novel exercise‐inducible myokine acidic ribosomal protein P2 (RPLP2), initially identified from human trials, is presented here, whose circulating levels negatively correlate with clinical anxiety severity. Muscle‐derived RPLP2 enhances hippocampal ribosomal assembly and adult neurogenesis to rescue stress‐induced anxiety deficits.
Peiyu Luo   +18 more
wiley   +1 more source

FLNeRF: 3D Facial Landmarks Estimation in Neural Radiance Fields [PDF]

open access: yes, 2023
This paper presents the first significant work on directly predicting 3D face landmarks on neural radiance fields (NeRFs). Our 3D coarse-to-fine Face Landmarks NeRF (FLNeRF) model efficiently samples from a given face NeRF with individual facial features
Tai, Yu-Wing   +3 more
core   +1 more source

Facial landmarks used to derive facial masculinity ratios.

open access: yes, 2016
Facial landmarks used to derive facial masculinity ratios.
Theodore Samore (3173523)   +4 more
core   +1 more source

Histone H3K18 Lactylation Promotes the Malignant Progression of Wilms Tumor via a PSRC1/AKT/HIF‐1α Positive Feedback Loop

open access: yesAdvanced Science, EarlyView.
In nephroblastoma, aberrant glycolysis drives lactate accumulation, which elevates histone H3K18 lactylation via p300. Lactylation of the PSRC1 promoter activates its transcription. PSRC1 competitively binds AKT, relieving PTEN‐mediated inhibition and triggering AKT/mTOR/HIF‐1α signaling.
Yanping Wang   +6 more
wiley   +1 more source

scTIDE: Deciphering Critical Transitions Through Cell‐Perturbed Manifold Graphs and Optimal Transport Conditional Flow Matching

open access: yesAdvanced Science, EarlyView.
scTIDE identifies single‐cell tipping points by combining manifold‐based graph representations with optimal‐transport conditional flow matching, which preserves intrinsic topology and models distributional dynamics. It supports critical‐transition detection at individual‐cell resolution, prediction of unseen cells, and dimensionality reduction and ...
Jiayuan Zhong   +6 more
wiley   +1 more source

A Dual‐Modal Wearable PPG Smartwatch with AI‐Enhanced Correction for High‐Accuracy and Continuous AF Burden Assessment

open access: yesAdvanced Science, EarlyView.
ABSTRACT Atrial fibrillation (AF) increases the risk of stroke and heart failure, yet accurate quantification of AF burden in daily life remains difficult. Although smartwatch photoplethysmography (PPG) supports continuous monitoring, complex rhythms and signal noise can impair burden estimation.
Song Zuo   +27 more
wiley   +1 more source

Failure Detection for Facial Landmark Detectors

open access: yesCoRR, 2016
Most face applications depend heavily on the accuracy of the face and facial landmarks detectors employed. Prediction of attributes such as gender, age, and identity usually completely fail when the faces are badly aligned due to inaccurate facial landmark detection.
Andreas Steger   +2 more
openaire   +3 more sources

The facial landmarks of the horse.

open access: yes, 2015
The facial landmarks of the horse.
Jen Wathan (780004)   +3 more
core   +1 more source

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