Results 101 to 110 of about 57,472 (341)

Intractable Facial Pain and Numb Chin due to Metastatic Esophageal Adenocarcinoma

Case Reports in Oncology, 2014
The etiologies of facial pain are innumerable, thus facial pain misdiagnosis and resultant mismanagement is common. Numb chin syndrome presents with hypoesthesia and/or anesthesia in the dermatomal distribution of the inferior alveolar or the mental ...
Foad Elahi, Whitney Luke, Fazel Elahi
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

TUMORS OF THE NOSE AND PARANASAL SINUSES IN CHILDREN, CLINICAL OBSERVATIONS

Žurnal Grodnenskogo Gosudarstvennogo Medicinskogo Universiteta, 2020
Resume. Neoplasms of the nasal cavity and perinasal sinuses at the beginning of their development are asymptomatic or non-specific symptoms may appear that mask them as inflammatory diseases (acute and chronic rhinosinusitis).
Rakova S. N., Halavach K. N., Logis O. V., Borodavko P. N., Bobrishev A. I.   +4 more
doaj   +1 more source

Unilateral hypertrophic skin lesions, hemimegalencephaly, and meningioma: The many faces of Proteus syndrome

Indian Dermatology Online Journal, 2015
Proteus syndrome is a rare condition with a wide spectrum of abnormalities. It is characterized by hamartomatous malformations involving multiple organs.
Niharika R Lal, Debabrata Bandyopadhyay, Asim K Sarkar   +2 more
doaj   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Indicações e técnicas cirúrgicas de reconstrução da face em neoplasias malignas / Indications and surgical techniques for facial reconstruction in malignant neoplasms [PDF]

, 2021
Carla Moreira Da Costa, Cibelle Maria Jacinta Da Silva, Gabriella Ludovico Fraga, Giovanna Gabrieli Aparecida Sousa Fazzolari, Júlia Fonseca Leão, Lucas Braga De Andrade, Wanessa Gonçalves Alves, Wagner Pablo Corrêa   +7 more
openalex   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Bilateral peripheral facial palsy secondary to lymphoma in a patient with HIV/AIDS: a case report and literature review

Brazilian Journal of Infectious Diseases
Neurological complications represent one of the most important causes of morbidity and mortality in patients with HIV/AIDS. However, peripheral neuropathy comprises only 5% to 20% of the total neurological complications and facial nerve palsy, especially
Maria das Graças Sasaki, Patrícia G. B. Leite, Andréa G. B. Leite, Sérgio Monteiro de Almeida   +3 more
doaj   +1 more source